Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 11/20 | 0.50 |
| ▸ | CDK9 | P50750 | 11/20 | 0.50 |
| ▸ | CDK2 | P24941 | 2/20 | 0.50 |
| ▸ | CCNC | P24863 | 1/20 | 0.49 |
| ▸ | CDK8 | P49336 | 1/20 | 0.49 |
| ▸ | FYN | P06241 | 3/20 | 0.48 |
| ▸ | CSF1R | P07333 | 3/20 | 0.46 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.41 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.41 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.41 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.41 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.41 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.41 |
| ▸ | CDK7 | P50613 | 1/20 | 0.40 |
| ▸ | BRAF | P15056 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12056837 | 1.00 | CCNT1 (0.50) | CCNT1CDK9CDK2CCNCCDK8 | |
| SCHEMBL12056821 | 1.00 | CCNT1 (0.50) | CCNT1CDK9CDK2CCNCCDK8 | |
| SCHEMBL12056900 | 0.92 | FYN (0.48) | CCNT1CDK9CDK2CCNCCDK8 | |
| SCHEMBL18286644 | 0.92 | CCNC (0.51) | CCNT1CDK9CDK2CCNCCDK8 | |
| SCHEMBL12056827 | 0.92 | CCNC (0.51) | CCNT1CDK9CDK2CCNCCDK8 | |
| SCHEMBL12056845 | 0.92 | CCNC (0.51) | CCNT1CDK9CDK2CCNCCDK8 | |
| SCHEMBL24411073 | 0.91 | FYN (0.60) | CCNT1CDK9CDK2CCNCCDK8 | |
| SCHEMBL12056823 | 0.91 | CCNC (0.50) | CCNT1CDK9CDK2CCNCCDK8 | |
| SCHEMBL12056841 | 0.91 | FYN (0.60) | CCNT1CDK9CDK2CCNCCDK8 | |
| SCHEMBL12056840 | 0.91 | CCNC (0.50) | CCNT1CDK9CDK2CCNCCDK8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022098808-A1 | THERAPEUTIC AGENTS FOR TREATING HEPATOCELLULAR CARCINOMA | ARIA PHARMACEUTICALS, INC. (US) | 2022-05-12 | — | — | WO | disclosed |
| EP-1569917-B1 | PYRAZINE-BASED TUBULIN INHIBITORS | YM BIOSCIENCES AUSTRALIA PTY (AU) | 2016-12-07 | — | — | EP | disclosed |