Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28087884 | 0.78 | KDM4E (0.31) | KDM4E | |
| SCHEMBL27587029 | 0.68 | — | — | |
| SCHEMBL10940131 | 0.68 | — | — | |
| SCHEMBL16181677 | 0.65 | KDM4E (0.30) | KDM4E | |
| SCHEMBL27677328 | 0.64 | — | — | |
| SCHEMBL27291893 | 0.62 | KDM4E (0.31) | KDM4E | |
| SCHEMBL27504677 | 0.62 | — | — | |
| SCHEMBL31534653 | 0.61 | KMT2A (0.32) | — | |
| SCHEMBL11363773 | 0.60 | — | — | |
| SCHEMBL28066475 | 0.60 | CCR2 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2654423-B1 | FUSED HETEROCYCLIC AZAINDANE CARBOXAMIDE CGRP RECEPTOR ANTAGONISTS | MERCK SHARP & DOHME (US) | 2016-12-07 | — | — | EP | disclosed |