SCHEMBL18289808

SCHEMBL18289808

CCN(CC)C(CCCNC(C)=O)C(N)=O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.44
MAPK1 P28482 1/20 0.44
HIF1A Q16665 1/20 0.44
PAOX Q6QHF9 3/20 0.42
ADRA1A P35348 1/20 0.37
SIRT5 Q9NXA8 2/20 0.35
FOLH1 Q04609 1/20 0.34
DPP7 Q9UHL4 2/20 0.33
ZDHHC7 Q9NXF8 1/20 0.33
TSHR P16473 1/20 0.33
MTNR1A P48039 1/20 0.33
MTNR1B P49286 1/20 0.33
SIRT6 Q8N6T7 1/20 0.33
SIRT1 Q96EB6 1/20 0.33
ALDH1A1 P00352 2/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
RRM1 P23921 1/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
MEN1 O00255 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18796569 0.85 ALOX15 (0.35) DPP7ALDH1A1RRM1CA1CA2
Hydrochloric Acid SCHEMBL18796568 0.84 ALOX15 (0.34) DPP7MEN1KMT2A
SCHEMBL20411600 0.78 KDM4E (0.50) KDM4EMAPK1HIF1APAOXADRA1A
SCHEMBL20411590 0.78 KDM4E (0.50) KDM4EMAPK1HIF1APAOXADRA1A
SCHEMBL20411598 0.78 KDM4E (0.50) KDM4EMAPK1HIF1APAOXADRA1A
SCHEMBL20411599 0.78 KDM4E (0.50) KDM4EMAPK1HIF1APAOXADRA1A
SCHEMBL20411715 0.78 KDM4E (0.50) KDM4EMAPK1HIF1APAOXADRA1A
SCHEMBL18289798 0.78 KDM4E (0.50) KDM4EMAPK1HIF1APAOXADRA1A
SCHEMBL20411594 0.78 KDM4E (0.50) KDM4EMAPK1HIF1APAOXADRA1A
SCHEMBL20411597 0.78 KDM4E (0.50) KDM4EMAPK1HIF1APAOXADRA1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2016196994-A1 REAGENTS FOR QUANTITATIVE MASS SPECTROMETRY PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2016-12-08 WO disclosed