Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 13/20 | 0.51 |
| ▸ | GGPS1 | O95749 | 5/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.40 |
| ▸ | PTGES | O14684 | 2/20 | 0.38 |
| ▸ | PNLIP | P16233 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | BCL9 | O00512 | 3/20 | 0.33 |
| ▸ | CTNNB1 | P35222 | 3/20 | 0.33 |
| ▸ | CETP | P11597 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18290241 | 0.81 | CYP19A1 (0.60) | FDPSGGPS1CYP19A1PTGESPNLIP | |
| SCHEMBL26230959 | 0.78 | FDPS (0.70) | FDPSGGPS1CYP19A1PTGESPNLIP | |
| Cryptojaponol SCHEMBL30600453 | 0.70 | FDPS (0.60) | FDPSGGPS1CYP19A1PTGESPNLIP | |
| Cryptojaponol SCHEMBL18290238 | 0.70 | FDPS (0.60) | FDPSGGPS1CYP19A1PTGESPNLIP | |
| Cryptojaponol SCHEMBL13532267 | 0.70 | FDPS (0.60) | FDPSGGPS1CYP19A1PTGESPNLIP | |
| Fortunin C SCHEMBL18290293 | 0.69 | FDPS (0.42) | FDPSGGPS1CYP19A1PTGESPNLIP | |
| SCHEMBL30061884 | 0.67 | FDPS (0.81) | FDPSGGPS1PTGESPNLIPMEN1 | |
| SCHEMBL22156381 | 0.66 | FDPS (0.69) | FDPSGGPS1PTGESPNLIPMEN1 | |
| Iguestol SCHEMBL18290360 | 0.65 | FDPS (0.40) | FDPSGGPS1CYP19A1PTGESPNLIP | |
| SCHEMBL6658577 | 0.65 | FDPS (0.80) | FDPSGGPS1CYP19A1PTGESPNLIP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016192631-A1 | ABIETANE-TYPE DITERPENE COMPOUND HAVING LIPID-LOWERING ACTIVITY, METHOD FOR PREPARING SAME, AND USE OF SAME | 中国科学院上海药物研究所 | 2016-12-08 | — | — | WO | disclosed |