Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | CTSK | P43235 | 10/20 | 0.45 |
| ▸ | CTSS | P25774 | 7/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | JAK3 | P52333 | 1/20 | 0.43 |
| ▸ | BTK | Q06187 | 1/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | CTSB | P07858 | 1/20 | 0.42 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26269789 | 0.84 | CTSK (0.43) | GAACTSKCTSSTDP1JAK3 | |
| SCHEMBL24924763 | 0.84 | CTSK (0.43) | GAACTSKCTSSTDP1JAK3 | |
| SCHEMBL26564159 | 0.83 | CTSK (0.43) | GAACTSKCTSSJAK3BTK | |
| SCHEMBL12156604 | 0.83 | MEN1 (0.53) | MEN1GAAKMT2ACTSKCTSS | |
| SCHEMBL2850443 | 0.83 | MEN1 (0.61) | MEN1GAAKMT2ACTSKCTSS | |
| SCHEMBL18281226 | 0.83 | MEN1 (0.61) | MEN1GAAKMT2ACTSKCTSS | |
| SCHEMBL1003435 | 0.83 | MEN1 (0.61) | MEN1GAAKMT2ACTSKCTSS | |
| SCHEMBL8163276 | 0.82 | JAK3 (0.44) | MEN1GAAKMT2ACTSKCTSS | |
| SCHEMBL16789185 | 0.81 | MEN1 (0.51) | MEN1GAAKMT2ACTSKCTSS | |
| SCHEMBL18354057 | 0.81 | GAA (0.44) | GAACTSKCTSSCTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016196393-A2 | AUTOPHAGY-INHIBITING COMPOUNDS AND USES THEREOF | PRESAGE BIOSCIENCES, INC. (US) | 2016-12-08 | — | — | WO | disclosed |