Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.70 |
| ▸ | NOX1 | Q9Y5S8 | 2/20 | 0.70 |
| ▸ | SMPD3 | Q9NY59 | 6/20 | 0.66 |
| ▸ | MPO | P05164 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 8/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | HPGD | P15428 | 2/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | HTT | P42858 | 1/20 | 0.64 |
| ▸ | TP53 | P04637 | 4/20 | 0.63 |
| ▸ | THRB | P10828 | 1/20 | 0.63 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.56 |
| ▸ | RAF1 | P04049 | 1/20 | 0.56 |
| ▸ | BRAF | P15056 | 1/20 | 0.56 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.56 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.56 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.56 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18292680 | 0.88 | NOX1 (0.78) | PTPN1NOX1SMPD3MPOMAPT | |
| SCHEMBL18292681 | 0.88 | SMPD3 (0.85) | NOX1SMPD3MPOMAPTTDP1 | |
| SCHEMBL14335897 | 0.85 | PTPN1 (0.69) | PTPN1NOX1SMPD3MPOMAPT | |
| SCHEMBL18292684 | 0.84 | MAPT (0.69) | NOX1SMPD3MPOMAPTTDP1 | |
| SCHEMBL12561702 | 0.83 | PTPN1 (1.00) | PTPN1NOX1SMPD3MAPTTP53 | |
| SCHEMBL1068914 | 0.83 | PTPN1 (0.94) | PTPN1NOX1SMPD3MAPTTP53 | |
| SCHEMBL6465030 | 0.83 | MAPK13 (0.71) | NOX1SMPD3MPOMAPTTDP1 | |
| SCHEMBL15075623 | 0.83 | MAPK13 (0.71) | NOX1SMPD3MPOMAPTTDP1 | |
| SCHEMBL8088592 | 0.83 | NOX1 (0.81) | PTPN1NOX1SMPD3MPOMAPT | |
| SCHEMBL18292686 | 0.82 | MAPT (0.73) | NOX1SMPD3MPOMAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160354375-A1 | CASEIN KINASE 1delta (CK 1delta) INHIBITORS AND THEIR USE IN THE TREATMENT OF NEURODEGENERATIVE DISEASES SUCH AS TAUOPATHIES | ELECTROPHORETICS LIMITED (GB) | 2016-12-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160354375-A1 | CASEIN KINASE 1delta (CK 1delta) INHIBITORS AND THEIR USE IN THE TREATMENT OF NEURODEGENERATIVE DISEASES SUCH AS TAUOPATHIES | CSNK1G1, CSNK1A1, CSNK1D | PTPN1 1275/4885NOX1 3444/4885SMPD3 2728/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.