SCHEMBL1829375

SCHEMBL1829375

C[CH]c1ccnnn1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4722330 0.76
SCHEMBL437702 0.75
SCHEMBL30275983 0.75
SCHEMBL27639135 0.75
SCHEMBL31295418 0.73
SCHEMBL4719860 0.72
SCHEMBL27712 0.70
SCHEMBL28228690 0.70
SCHEMBL8623922 0.70
SCHEMBL466310 0.67 MEN1 (0.63)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2318363-A1 HETEROCYCLIC DERIVATIVES AS IAP BINDING COMPOUNDS Nuevolution A/S (DK) 2011-05-11 EP claimed
WO-2009152824-A1 HETEROCYCLIC DERIVATIVES AS IAP BINDING COMPOUNDS NUEVOLUTION A/S (DK) 2009-12-23 WO claimed
US-7238697-B2 Pyridylpyrimidines for use as pesticides BAYER CROPSCIENCE AG (DE) 2007-07-03 US claimed
US-20040077641-A1 Pyridyl pyrimidines for use as pesticides BAYER CROPSCIENCE AG (DE) 2004-04-22 US claimed
EP-1367893-A1 PYRIDYL PYRIMIDINES FOR USE AS PESTICIDES Bayer CropScience AG (DE) 2003-12-10 EP claimed
WO-2002067684-A1 PYRIDYL PYRIMIDINES FOR USE AS PESTICIDES BAYER CROPSCIENCE AG (DE) 2002-09-06 WO claimed
EP-0571822-B1 Diazabicycloalkene derivatives DAIICHI SEIYAKU CO (JP) 2001-08-16 EP claimed
US-5418232-A Hypotensive, increases renal blood flow DAIICHI PHARMACEUTICAL CO., LTD. (JP) 1995-05-23 US claimed
CN-115956108-A Adhesive for endoscope, cured product thereof, endoscope, and method for producing endoscope 富士胶片株式会社 2023-04-11 CN disclosed
CN-106749268-B Heteroaromatic compounds and their use in medicine 广东东阳光药业有限公司 2020-10-09 CN disclosed
US-20140066369-A1 Modulators Of The GPR119 Receptor And The Treatment Of Disorders Related Thereto ARENA PHARMACEUTICALS, INC. (US) 2014-03-06 US disclosed
EP-1889836-B1 NOVEL PYRIDINE DERIVATIVE AND PYRIMIDINE DERIVATIVE (3) EISAI R&D MAN CO LTD (JP) 2013-06-12 EP disclosed
WO-2012145361-A1 MODULATORS OF THE GPR119 RECEPTOR AND THE TREATMENT OF DISORDERS RELATED THERETO ARENA PHARMACEUTICALS, INC. (US) 2012-10-26 WO disclosed
US-8288538-B2 Pyridine derivatives and pyrimidine derivatives (3) EISAI R&D MANAGEMENT CO., LTD. (JP) 2012-10-16 US disclosed
US-20040077641-A1 Pyridyl pyrimidines for use as pesticides BAYER CROPSCIENCE AG (DE) 2004-04-22 US disclosed
EP-1367893-A1 PYRIDYL PYRIMIDINES FOR USE AS PESTICIDES Bayer CropScience AG (DE) 2003-12-10 EP disclosed
WO-2002067684-A1 PYRIDYL PYRIMIDINES FOR USE AS PESTICIDES BAYER CROPSCIENCE AG (DE) 2002-09-06 WO disclosed
EP-0571822-B1 Diazabicycloalkene derivatives DAIICHI SEIYAKU CO (JP) 2001-08-16 EP disclosed
US-5418232-A Hypotensive, increases renal blood flow DAIICHI PHARMACEUTICAL CO., LTD. (JP) 1995-05-23 US disclosed
EP-0571822-A1 Diazabicycloalkene derivatives DAIICHI PHARMACEUTICAL CO., LTD. (JP) 1993-12-01 EP disclosed