Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 20/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18275323 | 0.92 | RORC (0.62) | RORC | |
| SCHEMBL18275325 | 0.90 | RORC (0.56) | RORC | |
| SCHEMBL18294272 | 0.90 | RORC (0.57) | RORC | |
| SCHEMBL18275264 | 0.89 | RORC (0.52) | RORC | |
| SCHEMBL18275330 | 0.88 | RORC (0.65) | RORC | |
| SCHEMBL18275230 | 0.87 | RORC (0.53) | RORC | |
| SCHEMBL18275336 | 0.86 | ABL1 (0.62) | RORC | |
| SCHEMBL18275317 | 0.86 | RORC (0.52) | RORC | |
| SCHEMBL18275253 | 0.85 | RORC (0.59) | RORC | |
| SCHEMBL18275209 | 0.85 | RORC (0.59) | RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016193452-A1 | ROR GAMMA (RORγ) MODULATORS | LEAD PHARMA CEL MODELS IP B.V. (NL) | 2016-12-08 | — | — | WO | disclosed |