SCHEMBL182943

SCHEMBL182943

CN1CCNC1=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5253568 1.00
Acetone SCHEMBL28628126 0.90 NPSR1 (0.44)
Phosphonic Acid SCHEMBL11347790 0.88 NPSR1 (0.39)
Pyrrole SCHEMBL11284691 0.86 KMT2A (0.40)
SCHEMBL791147 0.83
2-Pyrrolidone SCHEMBL1962942 0.82 OR51E2 (0.60)
SCHEMBL2743117 0.81
SCHEMBL24736816 0.79 KDM4E (0.42)
SCHEMBL8357683 0.79 KDM4E (0.42)
SCHEMBL23152961 0.79 KDM4E (0.42)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2591 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025104411-A1 THERAPEUTIC COMPOUNDS C4X DISCOVERY LIMITED (GB) 2025-05-22 WO claimed
US-20250143993-A1 COSMETIC SHISEIDO COMPANY, LTD. (JP) 2025-05-08 US claimed
US-12208088-B2 Spirocyclic 2,3-dihydro-7-azaindole compounds and uses thereof GENENTECH, INC. (US) 2025-01-28 US claimed
US-12187867-B2 PMMA-based cast polymers having improved mechanical properties EVONIK OPERATIONS GMBH (DE) 2025-01-07 US claimed
EP-4460307-A1 2,3-DIHYDROBENZO [B][1, 4]DIOXIN-2-YLMETHYL)PIPERAZIN-1-YL DERIVATES FOR THE TREATMENT OF SLEEP APNEA Bayer Aktiengesellschaft (DE) 2024-11-13 EP claimed
CN-118925943-A Spodumene ore floatation method 中国恩菲工程技术有限公司 2024-11-12 CN claimed
US-12103929-B2 Tricyclic compounds JACOBIO PHARMACEUTICALS CO., LTD. (CN) 2024-10-01 US claimed
CN-118501283-A Quick fishing method for traditional Chinese medicine active components based on multi-target proteins 云南中医药大学 2024-08-16 CN claimed
CN-118510514-A 2, 3-Dihydrobenzo [ b ] [1,4] dioxin-2-ylmethyl) piperazin-1-yl derivatives for the treatment of sleep apnea 拜耳公司 2024-08-16 CN claimed
CN-118401229-A Cosmetic material 株式会社资生堂 2024-07-26 CN claimed
US-6579881-B2 Indoles EISAI CO., LTD. (JP) 2003-06-17 US claimed
US-20030109556-A1 Melanocortin receptor ligands THE PROCTER & GAMBLE COMPANY 2003-06-12 US claimed
WO-2002085925-A2 MELANOCORTIN RECEPTOR LIGANDS THE PROCTER & GAMBLE COMPANY (US) 2002-10-31 WO claimed
US-6448243-B1 SEROTONIN ANTAGONIST FOR TREATING, AMELIORATING AND PREVENTING SPASTIC PARALYSIS OR CENTRAL MUSCLE RELAXANTS FOR AMELIORATING MYOTONIA EISAI CO., LTD. (JP) 2002-09-10 US claimed
US-20020086999-A1 Certain quinoline derivatives EISAI CO., LTD. 2002-07-04 US claimed
WO-2002032844-A2 EPOTHILONE SYNTHESIS COMPONENTS III AND IV: ASYMMETRICALLY SUBSTITUTED ACYLOINS AND ACYLOIN DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND METHOD FOR THE PRODUCTION OF EPITHILONE B, D AND EPOTHILONE DERIVATIVES MORPHOCHEM AG (DE) 2002-04-25 WO claimed
US-20020019531-A1 Indoles EISAI CO., LTD. 2002-02-14 US claimed
EP-0976732-A1 1,4-SUBSTITUTED CYCLIC AMINE DERIVATIVES Eisai Co., Ltd. (JP) 2000-02-02 EP claimed
EP-0743956-A4 PRETARGETING METHODS AND COMPOUNDS NEORX CORP (US) 1999-03-24 EP claimed
EP-0743956-A1 PRETARGETING METHODS AND COMPOUNDS NeoRx (US) 1996-11-27 EP claimed