Acetone

Acetone

SCHEMBL28628126

CC(C)=O.CN1CCNC1=O

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 1/20 0.44
TSHR P16473 1/20 0.39
FAAH O00519 1/20 0.38
NAAA Q02083 1/20 0.38
MAPT P10636 2/20 0.36
HTT P42858 1/20 0.36
ALDH1A1 P00352 2/20 0.35
POLB P06746 1/20 0.35
KMT2A Q03164 2/20 0.35
RAB9A P51151 1/20 0.35
GFER P55789 1/20 0.33
HSD17B10 Q99714 1/20 0.33
GAA P10253 1/20 0.32
PARP1 P09874 1/20 0.31
CRBN Q96SW2 1/20 0.31
BRD4 O60885 1/20 0.31
BRD2 P25440 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL182943 0.90
SCHEMBL5253568 0.90
Phosphonic Acid SCHEMBL11347790 0.84 NPSR1 (0.39) NPSR1TSHRFAAHNAAAMAPT
Acetic Acid SCHEMBL30239529 0.80 NPSR1 (0.37) NPSR1TSHRFAAHNAAAMAPT
Pyrrole SCHEMBL11284691 0.77 KMT2A (0.40) NPSR1TSHRFAAHNAAAMAPT
SCHEMBL791147 0.75
2-Pyrrolidone SCHEMBL1962942 0.74 OR51E2 (0.60) NPSR1TSHRPOLBKMT2AHSD17B10
SCHEMBL2743117 0.73
SCHEMBL23152961 0.71 KDM4E (0.42) NPSR1MAPTPOLBKMT2ARAB9A
SCHEMBL8357683 0.71 KDM4E (0.42) NPSR1MAPTPOLBKMT2ARAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113185463-A Ionic liquid compound, preparation method thereof and application of ionic liquid compound as extracting agent 苏州科技大学 2021-07-30 CN claimed