Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL973951 | 0.90 | HTR6 (0.40) | HTR6 | |
| SCHEMBL871079 | 0.90 | HTR6 (0.38) | HTR6 | |
| SCHEMBL3011186 | 0.86 | HTR6 (0.38) | HTR6 | |
| SCHEMBL3959219 | 0.86 | HTR6 (0.38) | HTR6 | |
| SCHEMBL1427870 | 0.85 | HTR6 (0.36) | HTR6 | |
| SCHEMBL139587 | 0.85 | HTR6 (0.41) | HTR6 | |
| SCHEMBL236429 | 0.85 | HTR6 (0.36) | HTR6 | |
| SCHEMBL129114 | 0.83 | HTR6 (0.39) | HTR6 | |
| SCHEMBL4823168 | 0.83 | HTR6 (0.39) | HTR6 | |
| SCHEMBL8717579 | 0.82 | HTR6 (0.36) | HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2318397-A2 | SUBSTITUTED INDOLE SULFONAMIDE COMPOUNDS, THEIR PREPARATION AND USE AS MEDICAMENTS | Laboratorios Del. Dr. Esteve, S.A. (ES) | 2011-05-11 | — | — | EP | disclosed |
| WO-2010012806-A2 | SUBSTITUTED INDOLE SULFONAMIDE COMPOUNDS, THEIR PREPARATION AND USE AS MEDICAMENTS | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2010-02-04 | — | — | WO | disclosed |
| EP-2149573-A1 | Substituted indole sulfonamide compounds their preparation and use as medicaments | Laboratorios Del. Dr. Esteve, S.A. (ES) | 2010-02-03 | — | — | EP | disclosed |
| EP-1947085-A1 | Substituted indole sulfonamide compounds, their preparation and use as medicaments | Laboratorios del Dr. Esteve S.A. (ES) | 2008-07-23 | — | — | EP | disclosed |