Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | F2 | P00734 | 1/20 | 0.48 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.48 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.48 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12658067 | 1.00 | KMT2A (0.54) | KMT2AL3MBTL1ALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL1828515 | 0.90 | SMN1; SMN2 (0.51) | KMT2AALDH1A1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL1828512 | 0.90 | SMN1; SMN2 (0.51) | KMT2AALDH1A1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL1831544 | 0.88 | KMT2A (0.53) | KMT2AALDH1A1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL1828432 | 0.88 | CA2 (0.50) | KMT2AALDH1A1SMN1; SMN2NPC1MEN1 | |
| SCHEMBL1832501 | 0.88 | KMT2A (0.53) | KMT2AALDH1A1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL1828592 | 0.88 | CA2 (0.50) | KMT2ASMN1; SMN2MEN1CA2F2 | |
| SCHEMBL1828593 | 0.88 | CA2 (0.50) | KMT2ASMN1; SMN2MEN1CA2F2 | |
| SCHEMBL1830014 | 0.88 | SMN1; SMN2 (0.53) | KMT2AL3MBTL1ALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL1830012 | 0.88 | SMN1; SMN2 (0.53) | KMT2AL3MBTL1ALDH1A1SMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1320520-B1 | SULFONYLGUANIDINE | GRUENENTHAL GMBH (DE) | 2011-05-11 | — | — | EP | claimed |