Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 3/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
| ▸ | SCARB1 | Q8WTV0 | 1/20 | 0.45 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18294836 | 0.98 | CNR2 (0.49) | CNR2OPRK1SCARB1ABCB1KDM4E | |
| SCHEMBL16880091 | 0.94 | OPRK1 (0.52) | OPRK1KDM4EGLAATMNPSR1 | |
| SCHEMBL18294868 | 0.90 | SCARB1 (0.46) | CNR2OPRK1SCARB1HRH1 | |
| Hydrochloric Acid SCHEMBL16880024 | 0.90 | SCARB1 (0.45) | CNR2OPRK1SCARB1HRH1 | |
| SCHEMBL16888558 | 0.89 | SCARB1 (0.48) | CNR2OPRK1SCARB1HRH1 | |
| SCHEMBL16880206 | 0.88 | HRH1 (0.44) | CNR2SCARB1HRH1 | |
| Hydrochloric Acid SCHEMBL16880109 | 0.88 | SCARB1 (0.47) | CNR2OPRK1SCARB1HRH1 | |
| SCHEMBL16879926 | 0.87 | HRH1 (0.42) | CNR2SCARB1HRH1 | |
| SCHEMBL16879907 | 0.87 | HDAC1 (0.44) | CNR2SCARB1KDM4ENPSR1 | |
| SCHEMBL16880036 | 0.86 | SCARB1 (0.44) | CNR2SCARB1HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160355475-A1 | NOVEL INDOLE DERIVATIVE COMPOUND AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2016-12-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160355475-A1 | NOVEL INDOLE DERIVATIVE COMPOUND AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | HDAC2, HDAC1, HDAC3 | CNR2 866/4885OPRK1 2122/4885SCARB1 4581/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.