Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.40 |
| ▸ | USP2 | O75604 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.36 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
| ▸ | FYN | P06241 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1793681 | 1.00 | ALDH1A1 (0.40) | ALDH1A1CYP3A4CYP2D6CYP1A2USP2 | |
| SCHEMBL1793924 | 0.97 | CYP2D6 (0.41) | ALDH1A1CYP3A4CYP2D6CYP1A2USP2 | |
| SCHEMBL11013028 | 0.94 | ALDH1A1 (0.44) | ALDH1A1CYP3A4CYP2D6CYP1A2USP2 | |
| SCHEMBL17609103 | 0.94 | ALDH1A1 (0.44) | ALDH1A1CYP3A4CYP2D6CYP1A2USP2 | |
| SCHEMBL7774907 | 0.94 | ALDH1A1 (0.44) | ALDH1A1CYP3A4CYP2D6CYP1A2USP2 | |
| SCHEMBL16878563 | 0.92 | ALDH1A1 (0.42) | ALDH1A1CYP3A4CYP2D6CYP1A2USP2 | |
| SCHEMBL17797726 | 0.92 | ALDH1A1 (0.42) | ALDH1A1CYP3A4CYP2D6CYP1A2USP2 | |
| SCHEMBL16878393 | 0.92 | ALDH1A1 (0.42) | ALDH1A1CYP3A4CYP2D6CYP1A2USP2 | |
| SCHEMBL1796659 | 0.91 | — | — | |
| SCHEMBL16878332 | 0.91 | ALDH1A1 (0.39) | ALDH1A1CYP3A4CYP2D6CYP1A2USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022200523-A9 | PHARMACEUTICAL COMPOUNDS AS INHIBITORS OF UBIQUITIN SPECIFIC PROTEASE 19 (USP19) | ALMAC DISCOVERY LIMITED (GB) | 2023-02-16 | — | — | WO | disclosed |
| US-20190263804-A1 | AZABENZIMIDAZOLE DERIVATIVES AS PI3K BETA INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2019-08-29 | — | — | US | disclosed |
| US-10202387-B2 | Heterocyclyl linked imidazopyridazine derivatives as PI3KB inhibitors | JANSSEN PHARMACEUTICA NV (BE) | 2019-02-12 | — | — | US | disclosed |
| US-20180057496-A1 | HETEROCYCLYL LINKED IMIDAZOPYRIDAZINE DERIVATIVES AS PI3KB INHIBITORS | JANSSEN-CILAG (FR) | 2018-03-01 | — | — | US | disclosed |
| US-20110230419-A1 | IAP BINDING COMPOUNDS | NUEVOLUTION A/S (DK) | 2011-09-22 | — | — | US | disclosed |
| EP-2318363-A1 | HETEROCYCLIC DERIVATIVES AS IAP BINDING COMPOUNDS | Nuevolution A/S (DK) | 2011-05-11 | — | — | EP | disclosed |
| WO-2009152824-A1 | HETEROCYCLIC DERIVATIVES AS IAP BINDING COMPOUNDS | NUEVOLUTION A/S (DK) | 2009-12-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190263804-A1 | AZABENZIMIDAZOLE DERIVATIVES AS PI3K BETA INHIBITORS | PIK3CD, PIK3CB, PIK3CA | ALDH1A1 1422/4885CYP3A4 344/4885CYP2D6 1100/4885 |
| US-10202387-B2 | Heterocyclyl linked imidazopyridazine derivatives as PI3KB inhibitors | PIK3CB, PIK3CD, PIK3CA | ALDH1A1 1880/4885CYP3A4 375/4885CYP2D6 741/4885 |
| US-20110230419-A1 | IAP BINDING COMPOUNDS | BIRC5, BIRC7, BIRC3 | ALDH1A1 2947/4885CYP3A4 3839/4885CYP2D6 3267/4885 |
| US-20180057496-A1 | HETEROCYCLYL LINKED IMIDAZOPYRIDAZINE DERIVATIVES AS PI3KB INHIBITORS | PIK3CB, PIK3CD, PIK3CA | ALDH1A1 1880/4885CYP3A4 375/4885CYP2D6 741/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.