Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | GLA | P06280 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | DGAT1 | O75907 | 9/20 | 0.46 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | PKMYT1 | Q99640 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3736028 | 0.93 | KMT2A (0.54) | KMT2AKDM4EGLAHTTSMN1; SMN2 | |
| SCHEMBL22048083 | 0.89 | KMT2A (0.53) | KMT2AKDM4EGLAHTTSMN1; SMN2 | |
| SCHEMBL1585290 | 0.83 | KDM4E (0.83) | KMT2AKDM4EGLAHTTSMN1; SMN2 | |
| SCHEMBL24316507 | 0.81 | KDM4E (0.60) | KMT2AKDM4EGLAHTTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL18036255 | 0.80 | KDM4E (0.50) | KMT2AKDM4EGLAHTTSMN1; SMN2 | |
| SCHEMBL13177598 | 0.79 | KDM4E (0.57) | KMT2AKDM4EGLAHTTSMN1; SMN2 | |
| SCHEMBL27174552 | 0.79 | KDM4E (0.57) | KMT2AKDM4EGLAHTTSMN1; SMN2 | |
| SCHEMBL14152280 | 0.77 | MAPK1 (0.57) | KMT2AKDM4EGLAHTTSMN1; SMN2 | |
| SCHEMBL25953857 | 0.77 | MAPK1 (0.57) | KMT2AKDM4EGLAHTTSMN1; SMN2 | |
| SCHEMBL14151857 | 0.76 | KDM4E (0.97) | KMT2AKDM4EGLAHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111601790-B | Heteroaryl compounds as protein kinase inhibitors | 福建海西新药创制股份有限公司 | 2023-03-31 | — | — | CN | claimed |
| WO-2026084434-A1 | 5-CYCLOPROPYLPICOLINAMIDE DERIVATIVE, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME FOR PREVENTNG OR TREATING CANCER | 에이치케이이노엔 주식회사 | 2026-04-23 | — | — | WO | disclosed |
| WO-2026084434-A1 | 5-CYCLOPROPYLPICOLINAMIDE DERIVATIVE, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME FOR PREVENTNG OR TREATING CANCER | 에이치케이이노엔 주식회사 | 2026-04-23 | — | — | WO | disclosed |
| CN-111601790-B | Heteroaryl compounds as protein kinase inhibitors | 福建海西新药创制股份有限公司 | 2023-03-31 | — | — | CN | disclosed |
| WO-2016196776-A2 | INHIBITORS OF BRUTON'S TYROSINE KINASE | PHARMACYCLICS LLC. (US) | 2016-12-08 | — | — | WO | disclosed |