SCHEMBL1829700

SCHEMBL1829700

Cc1ccc([N+](=O)[O-])c(Cl)c1C

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.55
TSHR P16473 8/20 0.53
SMN1; SMN2 Q16637 3/20 0.53
CRHBP P24387 1/20 0.49
CRHR2 Q13324 1/20 0.49
HSD17B10 Q99714 1/20 0.47
CYP3A4 P08684 2/20 0.46
ALDH1A1 P00352 2/20 0.46
CYP1A2 P05177 1/20 0.46
RECQL P46063 1/20 0.46
MAPK1 P28482 1/20 0.44
HTR2A P28223 2/20 0.44
HTR2C P28335 2/20 0.44
HTR2B P41595 2/20 0.44
MAPT P10636 2/20 0.43
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
KDM4E B2RXH2 1/20 0.40
LMNA P02545 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30904817 1.00 TDP1 (0.55) TDP1TSHRSMN1; SMN2CRHBPCRHR2
SCHEMBL5635692 0.85 TDP1 (0.63) TDP1TSHRSMN1; SMN2CRHBPCRHR2
SCHEMBL768285 0.83 TDP1 (0.54) TDP1TSHRSMN1; SMN2CRHBPCRHR2
SCHEMBL2910425 0.83 TDP1 (0.67) TDP1TSHRSMN1; SMN2CRHBPCRHR2
SCHEMBL29796095 0.83 TDP1 (0.54) TDP1TSHRSMN1; SMN2CRHBPCRHR2
SCHEMBL28911428 0.82 TSHR (0.55) TDP1TSHRSMN1; SMN2CRHBPCRHR2
SCHEMBL3192674 0.80 TSHR (0.65) TDP1TSHRSMN1; SMN2HSD17B10CYP3A4
SCHEMBL8335528 0.80 TDP1 (0.52) TDP1TSHRSMN1; SMN2CRHBPCRHR2
SCHEMBL10485141 0.80 TDP1 (0.52) TDP1TSHRSMN1; SMN2HSD17B10CYP3A4
SCHEMBL27935955 0.80 TDP1 (0.52) TDP1TSHRSMN1; SMN2CRHBPCRHR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118005017-B Preparation and application of bamboo activated carbon capable of serving as catalyst carrier 浙江佶竹生物科技有限公司 2024-07-09 CN disclosed
CN-118005017-A Preparation and application of bamboo activated carbon capable of serving as catalyst carrier 浙江佶竹生物科技有限公司 2024-05-10 CN disclosed
CN-102171190-A Insecticidal benzenedicarboxamide derivative BAYER CROPSCIENCE AG 2011-08-31 CN disclosed
US-20110184188-A1 Insecticidal Benzenedicarboxamide Derivative BAYER CROPSCIENCE AG (DE) 2011-07-28 US disclosed
EP-2318374-A2 INSECTICIDAL BENZENEDICARBOXAMIDE DERIVATIVE Bayer CropScience AG (DE) 2011-05-11 EP disclosed
CN-101679299-A Nicotinic acid derivatives as modulators of metabotropic glutamate receptor-5 NOVARTIS AG 2010-03-24 CN disclosed
WO-2010012442-A2 INSECTICIDAL BENZENEDICARBOXAMIDE DERIVATIVE BAYER CROPSCIENCE AG (DE) 2010-02-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110184188-A1 Insecticidal Benzenedicarboxamide Derivative DDT, BRD9, BCL2A1 TDP1 4411/4885TSHR 2047/4885SMN1; SMN2 3421/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.