Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 8/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 2/20 | 0.45 |
| ▸ | HTR2C | P28335 | 2/20 | 0.45 |
| ▸ | HTR2B | P41595 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28391943 | 0.86 | TDP1 (0.81) | TDP1TSHRCYP3A4ALDH1A1MAPK1 | |
| SCHEMBL30904817 | 0.85 | TDP1 (0.55) | TDP1HSD17B10TSHRCYP3A4ALDH1A1 | |
| SCHEMBL1829700 | 0.85 | TDP1 (0.55) | TDP1HSD17B10TSHRCYP3A4ALDH1A1 | |
| SCHEMBL768285 | 0.85 | TDP1 (0.54) | TDP1HSD17B10TSHRCYP3A4ALDH1A1 | |
| SCHEMBL29796095 | 0.85 | TDP1 (0.54) | TDP1HSD17B10TSHRCYP3A4ALDH1A1 | |
| SCHEMBL28911428 | 0.83 | TSHR (0.55) | TDP1HSD17B10TSHRCYP3A4ALDH1A1 | |
| SCHEMBL9452617 | 0.83 | TSHR (0.55) | TDP1HSD17B10TSHRCYP3A4ALDH1A1 | |
| SCHEMBL10485141 | 0.82 | TDP1 (0.52) | TDP1HSD17B10TSHRCYP3A4ALDH1A1 | |
| SCHEMBL5313608 | 0.82 | TSHR (0.52) | TDP1HSD17B10TSHRCYP3A4ALDH1A1 | |
| SCHEMBL20942954 | 0.82 | TDP1 (0.47) | TDP1HSD17B10TSHRCYP3A4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117003644-A | Novel method for synthesizing 2-chloro-6-nitrotoluene | 帕潘纳(北京)科技有限公司 | 2023-11-07 | — | — | CN | disclosed |
| CN-112266326-A | Preparation method of dichlorotoluene nitride intermediate | 杭州臻挚生物科技有限公司 | 2021-01-26 | — | — | CN | disclosed |
| US-20210005931-A1 | NONAQUEOUS ELECTROLYTE, ENERGY STORAGE DEVICE, AND METHOD FOR PRODUCING ENERGY STORAGE DEVICE | GS YUASA INTERNATIONAL LTD. (JP) | 2021-01-07 | — | — | US | disclosed |
| EP-3477758-B1 | NONAQUEOUS ELECTROLYTE, POWER STORAGE ELEMENT, AND METHOD FOR PRODUCING POWER STORAGE ELEMENT | GS YUASA INT LTD (JP) | 2020-12-16 | — | — | EP | disclosed |
| EP-3477758-A1 | NONAQUEOUS ELECTROLYTE, POWER STORAGE ELEMENT, AND METHOD FOR PRODUCING POWER STORAGE ELEMENT | GS Yuasa International Ltd. (JP) | 2019-05-01 | — | — | EP | disclosed |
| US-20070054912-A1 | Modulators of acetylcholine receptors | ASTLES PETER C | 2007-03-08 | — | — | US | disclosed |
| US-20050182088-A1 | Modulators of acetylcholine receptors | MERCK SHARP & DOHME CORP. | 2005-08-18 | — | — | US | disclosed |
| EP-1472248-A1 | MODULATORS OF ACETYLCHOLINE RECEPTORS | ELI LILLY AND COMPANY (US) | 2004-11-03 | — | — | EP | disclosed |
| WO-2003062235-A1 | MODULATORS OF ACETYLCHOLINE RECEPTORS | ELI LILLY AND COMPANY (US) | 2003-07-31 | — | — | WO | disclosed |
| US-6255542-B1 | RING CHLORINATING 4-NITROALKYLBENZENE WITH CHLORINE OR CHLORING-RELEASING AGENT IN A LIQUID PHASE AND IN THE PRESENCE OF A FRIEDEL-CRAFTS CATALYST AND A DIARYL SULFIDE CO-CATALYST | BAYER AKTIENGESELLSCHAFT (DE) | 2001-07-03 | — | — | US | disclosed |
| US-5801245-A | Process for the preparation of ethyl-N-(2,3 dichloro-6-nitrobenzyl) glycine | ROBERTS LABORATORIES INC. (US) | 1998-09-01 | — | — | US | disclosed |
| US-5095157-A | Friedel-crafts catalyst | BAYER AKTIENGESELLSCHAFT (DE) | 1992-03-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050182088-A1 | Modulators of acetylcholine receptors | CHRM3, CHRNG, CHRM5 | TDP1 970/4885HSD17B10 1779/4885TSHR 59/4885 |
| US-20070054912-A1 | Modulators of acetylcholine receptors | CHRM3, CHRNG, CHRM5 | TDP1 1721/4885HSD17B10 2070/4885TSHR 82/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.