Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | RET | P07949 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.34 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1829951 | 0.85 | PDE2A (0.35) | PDE2AHCRTR1HCRTR2 | |
| SCHEMBL1822437 | 0.83 | PDE2A (0.43) | PDE2AKDM4EALDH1A1HCRTR1HCRTR2 | |
| SCHEMBL8492410 | 0.79 | HCRTR1 (0.46) | HCRTR1CYP46A1HCRTR2 | |
| SCHEMBL5161145 | 0.74 | DHODH (0.43) | PDE2ALMNA | |
| SCHEMBL6488655 | 0.73 | PDE2A (0.37) | PDE2ALMNA | |
| SCHEMBL8817079 | 0.73 | KLKB1 (0.37) | PDE2AKMT2AKDM4EHCRTR1 | |
| SCHEMBL27513121 | 0.72 | DHODH (0.46) | PDE2ALMNA | |
| SCHEMBL8814987 | 0.71 | CSF1R (0.45) | PDE2AKMT2AALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL28105678 | 0.70 | NPC1 (0.47) | LMNAKMT2AKDM4EALDH1A1RXFP1 | |
| SCHEMBL1822485 | 0.69 | PDE2A (0.38) | PDE2ALMNAKDM4EALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2185536-B1 | HERBICIDE TRIAZOLYLPYRIDINE KETONES | BAYER CROPSCIENCE AG (DE) | 2011-05-04 | — | — | EP | disclosed |