Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 1/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 12/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 10/20 | 0.35 |
| ▸ | DHODH | Q02127 | 3/20 | 0.34 |
| ▸ | CRACR2A | Q9BSW2 | 2/20 | 0.33 |
| ▸ | KDM6B | O15054 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1829948 | 0.85 | PDE2A (0.37) | PDE2AHCRTR1HCRTR2 | |
| SCHEMBL1822437 | 0.81 | PDE2A (0.43) | PDE2AHCRTR1HCRTR2DHODHCRACR2A | |
| SCHEMBL5161145 | 0.74 | DHODH (0.43) | PDE2ADHODHCRACR2A | |
| SCHEMBL6488655 | 0.73 | PDE2A (0.37) | PDE2ADHODHCRACR2ANAMPT | |
| SCHEMBL27513121 | 0.72 | DHODH (0.46) | PDE2ADHODHCRACR2ANAMPT | |
| SCHEMBL28060968 | 0.69 | NOTUM (0.36) | HCRTR1HCRTR2 | |
| SCHEMBL9069970 | 0.69 | DHODH (0.36) | PDE2ADHODHCRACR2ANAMPT | |
| SCHEMBL8814987 | 0.68 | CSF1R (0.45) | PDE2ADHODHCRACR2A | |
| SCHEMBL8492072 | 0.68 | DHODH (0.38) | PDE2ADHODHCRACR2A | |
| SCHEMBL8814817 | 0.68 | GAA (0.39) | PDE2ADHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2185536-B1 | HERBICIDE TRIAZOLYLPYRIDINE KETONES | BAYER CROPSCIENCE AG (DE) | 2011-05-04 | — | — | EP | disclosed |