Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 11/20 | 0.55 |
| ▸ | TP53 | P04637 | 4/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.55 |
| ▸ | HRH1 | P35367 | 3/20 | 0.55 |
| ▸ | HTR2C | P28335 | 3/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.55 |
| ▸ | DRD4 | P21917 | 2/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | MTOR | P42345 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | KCNK9 | Q9NPC2 | 2/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.55 |
| ▸ | THPO | P40225 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | HTR7 | P34969 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29414105 | 0.83 | DRD2 (0.75) | DRD2TP53CYP3A4HRH1HTR2C | |
| SCHEMBL3837897 | 0.83 | DRD2 (0.75) | DRD2TP53CYP3A4HRH1HTR2C | |
| SCHEMBL7553968 | 0.79 | MAPT (0.62) | DRD2TP53CYP3A4HRH1HTR2C | |
| SCHEMBL11877802 | 0.77 | DRD2 (0.50) | DRD2TP53CYP3A4HRH1HTR2C | |
| SCHEMBL18310355 | 0.77 | DRD2 (0.69) | DRD2TP53CYP3A4HRH1HTR2C | |
| SCHEMBL11877811 | 0.76 | DRD2 (0.49) | DRD2TP53CYP3A4HRH1HTR2C | |
| SCHEMBL3688424 | 0.74 | MAPT (0.54) | DRD2TP53CYP3A4HRH1HTR2C | |
| Clorotepine SCHEMBL678917 | 0.71 | DRD2 (1.00) | DRD2TP53CYP3A4HRH1HTR2C | |
| Clorotepine SCHEMBL29822559 | 0.71 | DRD2 (1.00) | DRD2TP53CYP3A4HRH1HTR2C | |
| SCHEMBL10873797 | 0.71 | DRD2 (0.73) | DRD2TP53CYP3A4HRH1HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160361311-A1 | LIGANDS THAT TARGET HEPATITIS C VIRUS E2 PROTEIN | American University of Cairo (EG) | 2016-12-15 | — | — | US | disclosed |
| US-20160361311-A1 | LIGANDS THAT TARGET HEPATITIS C VIRUS E2 PROTEIN | American University of Cairo (EG) | 2016-12-15 | — | — | US | disclosed |
| US-20160361311-A1 | LIGANDS THAT TARGET HEPATITIS C VIRUS E2 PROTEIN | American University of Cairo (EG) | 2016-12-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160361311-A1 | LIGANDS THAT TARGET HEPATITIS C VIRUS E2 PROTEIN | CD81, HAVCR2, CTRL | DRD2 2441/4885TP53 456/4885CYP3A4 94/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.