Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12658062 | 1.00 | MAPK1 (0.46) | MAPK1CA2CA1CA9SMN1; SMN2 | |
| SCHEMBL1830250 | 1.00 | MAPK1 (0.46) | MAPK1CA2CA1CA9SMN1; SMN2 | |
| SCHEMBL1833219 | 0.87 | F2 (0.54) | CA2CA1SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL1833222 | 0.87 | F2 (0.54) | CA2CA1SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL12658168 | 0.87 | F2 (0.54) | CA2CA1SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL1828515 | 0.79 | SMN1; SMN2 (0.51) | CA2CA1SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL1828512 | 0.79 | SMN1; SMN2 (0.51) | CA2CA1SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL13438569 | 0.78 | F2 (0.54) | CA2CA1SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL1831727 | 0.78 | F2 (0.54) | CA2CA1SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL1831724 | 0.78 | F2 (0.54) | CA2CA1SMN1; SMN2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1320520-B1 | SULFONYLGUANIDINE | GRUENENTHAL GMBH (DE) | 2011-05-11 | — | — | EP | claimed |