Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.46 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 5/20 | 0.45 |
| ▸ | RAB9A | P51151 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MIF | P14174 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9778970 | 1.00 | MEN1 (0.50) | MEN1KMT2ACTDSP1PIN1NPC1 | |
| SCHEMBL10490150 | 1.00 | MEN1 (0.50) | MEN1KMT2ACTDSP1PIN1NPC1 | |
| SCHEMBL1959830 | 1.00 | MEN1 (0.50) | MEN1KMT2ACTDSP1PIN1NPC1 | |
| SCHEMBL29033269 | 0.87 | MIF (0.46) | MEN1KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL29176952 | 0.87 | MIF (0.46) | MEN1KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL9399429 | 0.86 | MIF (0.43) | MEN1KMT2ACTDSP1NPC1RAB9A | |
| SCHEMBL29033273 | 0.85 | NPC1 (0.47) | MEN1KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL29033185 | 0.84 | MAPT (0.44) | MEN1KMT2ARAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL9079738 | 0.84 | MAPT (0.44) | MEN1KMT2ARAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL29033272 | 0.84 | CYP1A2 (0.57) | MEN1KMT2ANPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110144336-A1 | Method for Preparation of Piperazindione Derivatives | BASF SE (DE) | 2011-06-16 | — | — | US | disclosed |
| EP-2318379-A1 | METHOD FOR PREPARATION OF PIPERAZINDIONE DERIVATES | BASF SE (DE) | 2011-05-11 | — | — | EP | disclosed |
| WO-2010018067-A1 | METHOD FOR PREPARATION OF PIPERAZINDIONE DERIVATES | BASF SE (DE) | 2010-02-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110144336-A1 | Method for Preparation of Piperazindione Derivatives | H1-0, H1-3, H1-2 | MEN1 3219/4885KMT2A 1804/4885CTDSP1 981/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.