Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | MIF | P14174 | 3/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | NOS3 | P29474 | 2/20 | 0.41 |
| ▸ | NOS1 | P29475 | 2/20 | 0.41 |
| ▸ | NOS2 | P35228 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29033185 | 1.00 | MAPT (0.44) | MAPTGAAMIFPPARGALDH1A1 | |
| SCHEMBL13664199 | 1.00 | MAPT (0.44) | MAPTGAAMIFPPARGALDH1A1 | |
| SCHEMBL9079735 | 1.00 | MAPT (0.44) | MAPTGAAMIFPPARGALDH1A1 | |
| SCHEMBL22854418 | 0.88 | NOS3 (0.41) | MAPTGAAMIFALDH1A1MEN1 | |
| SCHEMBL29033269 | 0.88 | MIF (0.46) | MAPTMIFPPARGALDH1A1LMNA | |
| SCHEMBL29176952 | 0.88 | MIF (0.46) | MAPTMIFPPARGALDH1A1LMNA | |
| SCHEMBL29033272 | 0.85 | CYP1A2 (0.57) | MAPTGAAMIFLMNATDP1 | |
| SCHEMBL7420415 | 0.84 | NOS2 (0.49) | MAPTMIFALDH1A1LMNAMEN1 | |
| SCHEMBL7420416 | 0.84 | NOS2 (0.49) | MAPTMIFALDH1A1LMNAMEN1 | |
| SCHEMBL6992245 | 0.84 | NOS2 (0.49) | MAPTMIFALDH1A1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5554753-A | Catalytic enantioselective synthesis of α-amino acid derivatives by phase-transfer catalysis | INDIANA UNIVERSITY FOUNDATION (US) | 1996-09-10 | — | — | US | disclosed |