SCHEMBL1830499

SCHEMBL1830499

OC(F)(C(F)(F)F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.42

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.42
THRB P10828 1/20 0.41
CA2 P00918 3/20 0.35
CA1 P00915 2/20 0.35
MMP1 P03956 2/20 0.35
MMP2 P08253 2/20 0.35
MMP9 P14780 2/20 0.35
MMP8 P22894 2/20 0.35
MMP13 P45452 2/20 0.35
F2 P00734 1/20 0.31
PRSS1 P07477 1/20 0.31
PRSS2 P07478 1/20 0.31
PRSS3 P35030 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5307190 1.00 LMNA (0.42) LMNATHRBCA2CA1MMP1
SCHEMBL3175397 1.00 LMNA (0.42) LMNATHRBCA2CA1MMP1
SCHEMBL7640246 1.00 LMNA (0.42) LMNATHRBCA2CA1MMP1
SCHEMBL1038814 1.00 LMNA (0.42) LMNATHRBCA2CA1MMP1
SCHEMBL11588704 1.00 LMNA (0.42) LMNATHRBCA2CA1MMP1
SCHEMBL970482 1.00 LMNA (0.42) LMNATHRBCA2CA1MMP1
SCHEMBL1830906 1.00 LMNA (0.42) LMNATHRBCA2CA1MMP1
SCHEMBL15641245 1.00 LMNA (0.42) LMNATHRBCA2CA1MMP1
SCHEMBL31548819 0.97 LMNA (0.40) LMNATHRBCA2CA1MMP1
SCHEMBL8617832 0.96 LMNA (0.37) LMNATHRBCA2CA1MMP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1703327-B1 Composition for forming antireflection film, laminate, and method for forming resist pattern JSR CORP (JP) 2011-05-11 EP disclosed
EP-1703327-A2 Composition for forming antireflection film, laminate, and method for forming resist pattern JSR Corporation (JP) 2006-09-20 EP disclosed