SCHEMBL183052

SCHEMBL183052

O=C(O)c1ccccc1N1C(=O)C=CC1=O

nearest known ligand 0.71

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.71
TLR9 Q9NR96 3/20 0.71
HSP90AA1 P07900 2/20 0.71
ATM Q13315 2/20 0.71
NPSR1 Q6W5P4 2/20 0.71
TDP1 Q9NUW8 2/20 0.71
PKM P14618 1/20 0.71
CCR6 P51684 1/20 0.71
ALOX15 P16050 1/20 0.56
MGLL Q99685 8/20 0.53
L3MBTL1 Q9Y468 2/20 0.53
GAA P10253 1/20 0.53
MYC P01106 3/20 0.52
NR4A1 P22736 1/20 0.52
APEX1 P27695 2/20 0.51
MITF O75030 1/20 0.51
HTT P42858 1/20 0.51
POLB P06746 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29364136 1.00 ALDH1A1 (0.71) ALDH1A1TLR9HSP90AA1ATMNPSR1
Hydrochloric Acid SCHEMBL6753288 0.98 ALDH1A1 (0.69) ALDH1A1TLR9HSP90AA1ATMNPSR1
Ethylene Glycol SCHEMBL11357029 0.93 ALDH1A1 (0.63) ALDH1A1TLR9HSP90AA1ATMNPSR1
SCHEMBL28343039 0.83 ALDH1A1 (0.56) ALDH1A1TLR9HSP90AA1ATMNPSR1
SCHEMBL29566884 0.83 ALDH1A1 (0.56) ALDH1A1TLR9HSP90AA1ATMNPSR1
SCHEMBL26659336 0.83 ALDH1A1 (0.56) ALDH1A1TLR9HSP90AA1ATMNPSR1
SCHEMBL1673297 0.83 TLR9 (1.00) ALDH1A1TLR9HSP90AA1ATMNPSR1
SCHEMBL10935998 0.83 TLR9 (0.56) ALDH1A1TLR9HSP90AA1ATMNPSR1
SCHEMBL10938557 0.82 ALDH1A1 (0.64) ALDH1A1TLR9HSP90AA1ATMNPSR1
SCHEMBL7165238 0.82 TLR9 (0.64) ALDH1A1TLR9HSP90AA1ATMNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 946 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260001891-A1 FUSED RING COMPOUND, CONJUGATE THEREOF AND USE THEREOF KEYMED BIOSCIENCES (CHENGDU) CO., LTD. (CN) 2026-01-01 US claimed
CN-118048034-B Nano silicon dioxide modified ABS alloy composite material and preparation method thereof 广州豫顺新材料科技有限公司 2024-06-14 CN claimed
CN-118048034-A Nano silicon dioxide modified ABS alloy composite material and preparation method thereof 广州豫顺新材料科技有限公司 2024-05-17 CN claimed
CN-110418783-B Process for purifying N-substituted maleimides 株式会社LG化学 2022-10-04 CN claimed
CN-110198927-B Process for purifying N-substituted maleimides 株式会社LG化学 2022-08-12 CN claimed
EP-3636634-B1 METHOD FOR PURIFYING N-SUBSTITUTED MALEIMIDE LG CHEMICAL LTD (KR) 2022-06-22 EP claimed
CN-109071432-B Synthesis method of N-substituted maleimide by using solid acid catalyst 株式会社LG化学 2022-04-12 CN claimed
US-11117100-B2 Hydrophilic polymer and membrane for oil-water separation and method of producing the same NGEE ANN POLYTECHNIC (SG) 2021-09-14 US claimed
EP-3148577-B1 NOVEL SEMI-SYNTHETIC MENINGOCOCCAL CONJUGATE VACCINE BIOLOGICAL E LTD (IN) 2021-01-20 EP claimed
EP-3578544-B1 METHOD FOR PURIFYING N-SUBSTITUTED MALEIMIDE LG CHEMICAL LTD (KR) 2020-12-30 EP claimed
EP-0262796-B1 Resin compositons and their manufacturing method TORAY INDUSTRIES (JP) 1993-11-03 EP claimed
EP-0336856-B1 WITH MALEIMIDE GROUPS FUNCTIONALIZED AROMATIC POLYAMIDEIMIDES, PROCESS FOR THEIR PREPARATION AND THEIR USE FOR PREPARING CROSS-LINKED POLYMERS CIBA-GEIGY AG (CH) 1993-03-03 EP claimed
US-5164440-A Blend of polyamide, layered silicate, impact improver UBE INDUSTRIES, LTD. (JP) 1992-11-17 US claimed
US-5164425-A Allyl terminated polyesters, fillers SHOWA DENKO K.K. (JP) 1992-11-17 US claimed
EP-0493631-A1 Artificial marble composition SHOWA DENKO KABUSHIKI KAISHA (JP) 1992-07-08 EP claimed
EP-0230597-B1 METHOD FOR INHIBITING POLYMERIZATION OF MALEIMIDES Nippon Shokubai Kagaku Kogyo Co., Ltd (JP) 1992-04-08 EP claimed
US-5096948-A Maleimide copolymer, hindered amine stabilizer, discoloration inhibition SANKYO COMPANY, LIMITED (JP) 1992-03-17 US claimed
US-4927900-A Aromatic polyamidoimides having maleimido end groups RHONE-POULENC CHIMIE (FR) 1990-05-22 US claimed
EP-0262796-A2 Resin compositons and their manufacturing method TORAY INDUSTRIES, INC. (JP) 1988-04-06 EP claimed
US-4731439-A Snake venom growth arresting peptide ONCOGEN (US) 1988-03-15 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260001891-A1 FUSED RING COMPOUND, CONJUGATE THEREOF AND USE THEREOF HCCS, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, CBR1 ALDH1A1 516/4885TLR9 2231/4885HSP90AA1 2215/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.