Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC5A1 | P13866 | 8/20 | 0.77 |
| ▸ | SLC5A2 | P31639 | 8/20 | 0.77 |
| ▸ | MAPT | P10636 | 4/20 | 0.59 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.59 |
| ▸ | GAA | P10253 | 3/20 | 0.59 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.59 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.59 |
| ▸ | RELA | Q04206 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | TTR | P02766 | 1/20 | 0.59 |
| ▸ | ESR1 | P03372 | 1/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18306234 | 0.89 | SLC5A1 (0.84) | SLC5A1SLC5A2MAPTCYP19A1GAA | |
| SCHEMBL26244512 | 0.87 | SLC5A1 (0.78) | SLC5A1SLC5A2MAPTCYP19A1GAA | |
| SCHEMBL458222 | 0.87 | SLC5A1 (1.00) | SLC5A1SLC5A2MAPTCYP19A1GAA | |
| SCHEMBL18306227 | 0.86 | SLC5A1 (0.69) | SLC5A1SLC5A2MAPTCYP19A1GAA | |
| SCHEMBL18306224 | 0.84 | SLC5A1 (0.68) | SLC5A1SLC5A2MAPTCYP19A1GAA | |
| SCHEMBL18306226 | 0.84 | SLC5A1 (0.68) | SLC5A1SLC5A2MAPTCYP19A1GAA | |
| SCHEMBL1682159 | 0.83 | NFKB1 (0.83) | SLC5A1SLC5A2MAPTCYP19A1GAA | |
| SCHEMBL18306228 | 0.82 | SLC5A1 (0.64) | SLC5A1SLC5A2MAPTCYP19A1GAA | |
| SCHEMBL18306233 | 0.82 | SLC5A1 (0.64) | SLC5A1SLC5A2MAPTCYP19A1GAA | |
| SCHEMBL457501 | 0.81 | SLC5A1 (1.00) | SLC5A1SLC5A2MAPTCYP19A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9517994-B2 | Antibacterial agents: phloroglucinol derivatives | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2016-12-13 | — | — | US | disclosed |