Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.55 |
| ▸ | RAB9A | P51151 | 7/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | ALPL | P05186 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.48 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8350294 | 0.84 | MAPT (0.56) | MAPTRAB9ASMN1; SMN2NPC1MEN1 | |
| SCHEMBL102052 | 0.82 | MAPT (0.58) | MAPTRAB9ASMN1; SMN2NPC1MEN1 | |
| SCHEMBL23531016 | 0.82 | MAPT (0.55) | MAPTRAB9ASMN1; SMN2NPC1MEN1 | |
| SCHEMBL103693 | 0.82 | MAPT (0.55) | MAPTRAB9ASMN1; SMN2NPC1MEN1 | |
| SCHEMBL9570471 | 0.82 | MAPT (0.55) | MAPTRAB9ASMN1; SMN2NPC1MEN1 | |
| Hydrochloric Acid SCHEMBL31312462 | 0.81 | MAPT (0.54) | MAPTRAB9ASMN1; SMN2NPC1MEN1 | |
| SCHEMBL10515790 | 0.77 | RAB9A (0.54) | MAPTRAB9ASMN1; SMN2NPC1MEN1 | |
| SCHEMBL102089 | 0.76 | MAPT (0.49) | MAPTRAB9ASMN1; SMN2NPC1MEN1 | |
| SCHEMBL7947747 | 0.75 | GAA (0.50) | MAPTRAB9ASMN1; SMN2NPC1MEN1 | |
| SCHEMBL104116 | 0.72 | MAPT (0.47) | MAPTRAB9ASMN1; SMN2NPC1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3103450-A1 | NONE-HYDROPHOBIC COMPOUNDS FOR USE IN TREATING METASTASIS AND/OR CARTILAGE DEFECT | Friedrich-Alexander-Universität Erlangen-Nürnberg (DE) | 2016-12-14 | — | — | EP | disclosed |