Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.82 |
| ▸ | SIRT2 | Q8IXJ6 | 4/20 | 0.70 |
| ▸ | LMNA | P02545 | 3/20 | 0.69 |
| ▸ | USP2 | O75604 | 2/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 4/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22640037 | 0.86 | MAPT (0.85) | MAPTSIRT2LMNATSHRSMN1; SMN2 | |
| SCHEMBL20067965 | 0.86 | SIRT2 (0.79) | MAPTSIRT2LMNAUSP2SMN1; SMN2 | |
| SCHEMBL20068003 | 0.83 | SIRT2 (0.71) | MAPTSIRT2LMNAUSP2SMN1; SMN2 | |
| SCHEMBL20067938 | 0.83 | SIRT2 (0.70) | MAPTSIRT2LMNASMN1; SMN2GAA | |
| SCHEMBL20067976 | 0.82 | SIRT2 (0.69) | MAPTSIRT2LMNASMN1; SMN2GAA | |
| SCHEMBL20068107 | 0.82 | SIRT2 (1.00) | MAPTSIRT2LMNAUSP2SMN1; SMN2 | |
| SCHEMBL20068030 | 0.81 | SIRT2 (0.72) | MAPTSIRT2LMNAUSP2TSHR | |
| SCHEMBL20067944 | 0.81 | SIRT2 (0.72) | MAPTSIRT2LMNAUSP2SMN1; SMN2 | |
| SCHEMBL20067928 | 0.81 | SIRT2 (0.76) | MAPTSIRT2LMNAUSP2SMN1; SMN2 | |
| SCHEMBL20067930 | 0.81 | SIRT2 (0.74) | MAPTSIRT2LMNAUSP2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3103450-A1 | NONE-HYDROPHOBIC COMPOUNDS FOR USE IN TREATING METASTASIS AND/OR CARTILAGE DEFECT | Friedrich-Alexander-Universität Erlangen-Nürnberg (DE) | 2016-12-14 | — | — | EP | disclosed |