Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.50 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | PLA2G2C | Q5R387 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TLR2 | O60603 | 2/20 | 0.37 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | MMP8 | P22894 | 1/20 | 0.35 |
| ▸ | MMP14 | P50281 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 4/20 | 0.34 |
| ▸ | S1PR2 | O95136 | 3/20 | 0.34 |
| ▸ | S1PR5 | Q9H228 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6417565 | 0.75 | MEN1 (0.41) | EPHX1MEN1KMT2AALDH1A1POLB | |
| SCHEMBL19577778 | 0.73 | EPHX1 (0.34) | EPHX1MEN1KMT2AALDH1A1POLB | |
| SCHEMBL13864345 | 0.71 | KMT2A (0.51) | EPHX1MEN1KMT2AALDH1A1POLB | |
| SCHEMBL17769633 | 0.71 | EPHX1 (0.36) | EPHX1MEN1KMT2AALDH1A1POLB | |
| SCHEMBL14538819 | 0.71 | EPHX1 (0.49) | EPHX1MEN1KMT2AALDH1A1POLB | |
| SCHEMBL7716931 | 0.70 | EPHX1 (1.00) | EPHX1CES2MEN1KMT2AALDH1A1 | |
| SCHEMBL10688529 | 0.70 | EPHX1 (1.00) | EPHX1CES2MEN1KMT2AALDH1A1 | |
| SCHEMBL13010044 | 0.70 | EPHX1 (1.00) | EPHX1CES2MEN1KMT2AALDH1A1 | |
| SCHEMBL10683800 | 0.70 | EPHX1 (1.00) | EPHX1CES2MEN1KMT2AALDH1A1 | |
| SCHEMBL10690536 | 0.70 | EPHX1 (1.00) | EPHX1CES2MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2256133-B1 | Bioconjugation of macromolecules | SIGMA ALDRICH CO LLC (US) | 2016-12-14 | — | — | EP | disclosed |