Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 8/20 | 1.00 |
| ▸ | MEN1 | O00255 | 2/20 | 0.79 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.79 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.75 |
| ▸ | POLB | P06746 | 1/20 | 0.75 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.75 |
| ▸ | CA3 | P07451 | 2/20 | 0.64 |
| ▸ | CA5A | P35218 | 2/20 | 0.64 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.64 |
| ▸ | CA12 | O43570 | 1/20 | 0.64 |
| ▸ | CA2 | P00918 | 1/20 | 0.64 |
| ▸ | CA4 | P22748 | 1/20 | 0.64 |
| ▸ | CA6 | P23280 | 1/20 | 0.64 |
| ▸ | CA7 | P43166 | 1/20 | 0.64 |
| ▸ | CA9 | Q16790 | 1/20 | 0.64 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.64 |
| ▸ | MLYCD | O95822 | 1/20 | 0.54 |
| ▸ | CASP2 | P42575 | 1/20 | 0.53 |
| ▸ | FAAH | O00519 | 5/20 | 0.50 |
| ▸ | CES1 | P23141 | 4/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7716931 | 1.00 | EPHX1 (1.00) | EPHX1MEN1KMT2AALDH1A1POLB | |
| SCHEMBL10683800 | 1.00 | EPHX1 (1.00) | EPHX1MEN1KMT2AALDH1A1POLB | |
| SCHEMBL10685206 | 1.00 | EPHX1 (1.00) | EPHX1MEN1KMT2AALDH1A1POLB | |
| SCHEMBL5057808 | 1.00 | EPHX1 (1.00) | EPHX1MEN1KMT2AALDH1A1POLB | |
| SCHEMBL11475528 | 1.00 | EPHX1 (1.00) | EPHX1MEN1KMT2AALDH1A1POLB | |
| SCHEMBL10688529 | 1.00 | EPHX1 (1.00) | EPHX1MEN1KMT2AALDH1A1POLB | |
| SCHEMBL10690536 | 1.00 | EPHX1 (1.00) | EPHX1MEN1KMT2AALDH1A1POLB | |
| SCHEMBL1389225 | 0.98 | EPHX1 (0.96) | EPHX1MEN1KMT2AALDH1A1POLB | |
| SCHEMBL2736707 | 0.91 | EPHX1 (0.84) | EPHX1MEN1KMT2AALDH1A1POLB | |
| SCHEMBL7545639 | 0.89 | EPHX1 (0.80) | EPHX1MEN1KMT2AALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190077726-A1 | METHODS OF SYNTHESIZING LABELED NUCLEOSIDES | SINGULAR GENOMICS SYSTEMS INC (US) | 2019-03-14 | — | — | US | disclosed |
| US-20170355727-A1 | CONJUGATED ANTISENSE COMPOUNDS AND THEIR USE | IONIS PHARMACEUTICALS, INC. (US) | 2017-12-14 | — | — | US | disclosed |
| US-20100317714-A1 | COMPLEX MOLECULE INTERFERING THE EXPRESSION OF TARGET GENES AND ITS PREPARING METHODS | SUZHOU RIBO LIFE SCIENCE CO., LTD (CN) | 2010-12-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190077726-A1 | METHODS OF SYNTHESIZING LABELED NUCLEOSIDES | NUDT1, DUT, PNP | EPHX1 1504/4885MEN1 2668/4885KMT2A 2754/4885 |
| US-20170355727-A1 | CONJUGATED ANTISENSE COMPOUNDS AND THEIR USE | GNE, GALNT1, GALNT6 | EPHX1 4222/4885MEN1 2964/4885KMT2A 1653/4885 |
| US-20100317714-A1 | COMPLEX MOLECULE INTERFERING THE EXPRESSION OF TARGET GENES AND ITS PREPARING METHODS | DCLRE1B, RNASE1, AGO2 | EPHX1 2667/4885MEN1 1287/4885KMT2A 1397/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.