Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A2 | P43004 | 1/20 | 0.43 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.43 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.43 |
| ▸ | GABRP | O00591 | 1/20 | 0.43 |
| ▸ | GABRD | O14764 | 1/20 | 0.43 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.43 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.43 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.43 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.43 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.43 |
| ▸ | GABRE | P78334 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.43 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.43 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.43 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.43 |
| ▸ | SLC6A1 | P30531 | 4/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13439403 | 1.00 | SLC1A2 (0.43) | SLC1A2GABRA5GABRB2TSHRGABRA1 | |
| SCHEMBL4001723 | 1.00 | SLC1A2 (0.43) | SLC1A2GABRA5GABRB2TSHRGABRA1 | |
| SCHEMBL4009207 | 1.00 | SLC1A2 (0.43) | SLC1A2GABRA5GABRB2TSHRGABRA1 | |
| SCHEMBL2312750 | 1.00 | SLC1A2 (0.43) | SLC1A2GABRA5GABRB2TSHRGABRA1 | |
| SCHEMBL22863934 | 1.00 | SLC1A2 (0.43) | SLC1A2GABRA5GABRB2TSHRGABRA1 | |
| SCHEMBL3027763 | 1.00 | SLC1A2 (0.43) | SLC1A2GABRA5GABRB2TSHRGABRA1 | |
| Hydrochloric Acid SCHEMBL2158140 | 0.98 | SLC1A2 (0.42) | SLC1A2GABRA5GABRB2TSHRGABRA1 | |
| Hydrochloric Acid SCHEMBL2158135 | 0.98 | SLC1A2 (0.42) | SLC1A2GABRA5GABRB2TSHRGABRA1 | |
| Hydrochloric Acid SCHEMBL2158131 | 0.98 | SLC1A2 (0.42) | SLC1A2GABRA5GABRB2TSHRGABRA1 | |
| SCHEMBL16584219 | 0.83 | GABRA5 (0.43) | SLC1A2GABRA5GABRB2TSHRGABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4712961-A2 | KRAS G12S AND G12C INHIBITORS | Mirati Therapeutics, Inc. (US) | 2026-03-25 | — | — | EP | disclosed |
| WO-2024238633-A2 | KRAS G12S AND G12C INHIBITORS | Mirati Therapeutics, Inc. (US) | 2024-11-21 | — | — | WO | disclosed |
| WO-2016200851-A1 | NUCLEAR RECEPTOR MODULATORS | ABBVIE INC. (US) | 2016-12-15 | — | — | WO | disclosed |