Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9156224 | 0.79 | APLNR (0.36) | APLNR | |
| SCHEMBL25307674 | 0.78 | APLNR (0.37) | APLNR | |
| SCHEMBL22907 | 0.74 | APLNR (0.55) | APLNR | |
| SCHEMBL16718804 | 0.74 | APLNR (0.55) | APLNR | |
| SCHEMBL15536695 | 0.74 | TSHR (0.33) | — | |
| SCHEMBL26980842 | 0.72 | APLNR (0.46) | APLNR | |
| SCHEMBL3060885 | 0.71 | POLB (0.33) | APLNR | |
| SCHEMBL16886414 | 0.71 | POLB (0.33) | APLNR | |
| SCHEMBL16875514 | 0.71 | POLB (0.33) | APLNR | |
| SCHEMBL3025238 | 0.70 | APLNR (0.38) | APLNR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2855428-A1 | N-SUBSTITUTED BENZAMIDES AND THEIR USE IN THE TREATMENT OF PAIN | Genentech, Inc. (US) | 2015-04-08 | — | — | EP | disclosed |
| WO-2013177224-A1 | N-SUBSTITUTED BENZAMIDES AND THEIR USE IN THE TREATMENT OF PAIN | GENENTECH, INC. (US) | 2013-11-28 | — | — | WO | disclosed |
| WO-2012025857-A1 | CYCLOALKYL METHOXYBENZYL PHENYL PYRAN DERIVATIVES AS SODIUM DEPENDENT GLUCOSE CO TRANSPORTER (SGLT2) INHIBITORS | HETERO RESEARCH FOUNDATION (IN) | 2012-03-01 | — | — | WO | disclosed |