SCHEMBL183118

SCHEMBL183118

Nc1nc(N)nc(Nc2ccccc2)n1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 4/20 0.68
RAB9A P51151 4/20 0.68
MAPT P10636 3/20 0.68
KMT2A Q03164 3/20 0.68
HTT P42858 2/20 0.68
BCL6 P41182 1/20 0.66
GAA P10253 4/20 0.63
MEN1 O00255 2/20 0.63
KDM4E B2RXH2 2/20 0.63
NFKB1 P19838 2/20 0.57
MAPK1 P28482 2/20 0.57
SMN1; SMN2 Q16637 3/20 0.56
TSHR P16473 2/20 0.56
TP53 P04637 1/20 0.56
PKM P14618 1/20 0.56
ALOX15 P16050 1/20 0.56
NFKB2 Q00653 1/20 0.56
RELA Q04206 1/20 0.56
TAAR1 Q96RJ0 1/20 0.56
CA12 O43570 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29900287 1.00 NPC1 (0.68) NPC1RAB9AMAPTKMT2AHTT
Hydrochloric Acid SCHEMBL9457998 0.98 NPC1 (0.66) NPC1RAB9AMAPTKMT2AHTT
Arsenic SCHEMBL28153612 0.98 NPC1 (0.66) NPC1RAB9AMAPTKMT2AHTT
SCHEMBL29079539 0.96 MAPT (0.64) NPC1RAB9AMAPTKMT2AHTT
SCHEMBL2253957 0.95 GAA (0.69) NPC1RAB9AMAPTKMT2AHTT
Aniline SCHEMBL27966308 0.94 MAPT (0.62) NPC1RAB9AMAPTKMT2AHTT
SCHEMBL10910614 0.88 CA12 (0.68) NPC1RAB9AMAPTKMT2AHTT
SCHEMBL29610073 0.86 GAA (0.74) NPC1RAB9AMAPTKMT2AHTT
SCHEMBL14869446 0.86 GAA (0.74) NPC1RAB9AMAPTKMT2AHTT
SCHEMBL796156 0.86 BCL6 (0.61) NPC1RAB9AMAPTKMT2AHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 665 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119932930-A Manufacturing process and equipment of flame-retardant canvas 台州市易思纺织品有限公司 2025-05-06 CN claimed
CN-118852921-A Environment-friendly flexible enamel anticorrosive paint and preparation method thereof 上海同恒海泰新材料科技发展有限公司 2024-10-29 CN claimed
CN-115472911-A Electrolyte, secondary battery and electric device 欣旺达电动汽车电池有限公司 2022-12-13 CN claimed
CN-112366351-B Lithium-supplementing slow-release capsule, electrolyte thereof and lithium ion battery 山东海科创新研究院有限公司 2021-12-03 CN claimed
CN-112366351-A Lithium-supplementing slow-release capsule, electrolyte thereof and lithium ion battery 山东海科创新研究院有限公司 2021-02-12 CN claimed
CN-105377225-A Uv compositions having low active concentrations and high in vivo spf PROCTER & GAMBLE 2016-03-02 CN claimed
CN-101981122-B Polyacetal resin composition MITSUBISHI GAS CHEMICAL CO 2013-05-15 CN claimed
US-20100137467-A1 POLYURETHANE FOAM CONTAINING FLAME-RETARDANT MIXTURE ICL-IP AMERICA INC. 2010-06-03 US claimed
EP-2091991-A2 POLYURETHANE FOAM CONTAINING FLAME-RETARDANT MIXTURE Supresta LLC (US) 2009-08-26 EP claimed
WO-2008118154-A2 POLYURETHANE FOAM CONTAINING FLAME-RETARDANT MIXTURE SUPRESTA LLC (US) 2008-10-02 WO claimed
EP-0437186-B1 Melamine derivatives as stabilizers for chlorine containing polymers CIBA GEIGY AG (CH) 1995-12-06 EP claimed
US-5272192-A Melamine derivatives as stabilizers for chloride-containing polymers CIBA-GEIGY CORPORATION (US) 1993-12-21 US claimed
EP-0437186-A1 Melamine derivatives as stabilizers for chlorine containing polymers CIBA-GEIGY AG (CH) 1991-07-17 EP claimed
US-4942191-A Urea-FORMALDEHYDE OR PHENOL-FORMALDEHYDE RESIN FOR LAMINATION OF LIGNOCELLULOSE MATERIALS SUCH AS WOOD BORDEN, INC. (US) 1990-07-17 US claimed
CN-121623760-A Preparation process of graphene-reinforced porous composite filter material of fume hood for waste gas purification 安徽省义广实验室装备制造有限公司 2026-03-10 CN disclosed
US-12569911-B2 Composition for use in sintered molded bodies and sintered molded body ASAHI KASEI KABUSHIKI KAISHA (JP) 2026-03-10 US disclosed
EP-4674879-A1 CATIONIC POLYMERIZATION INITIATOR COMPOSITION, AND METHOD FOR PRODUCING OXYMETHYLENE COPOLYMER AND MOLDED ARTICLE USING SAME MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2026-01-07 EP disclosed
US-4339578-A STABILIZERS FOR FORMALDEHYDE DEGUSSA AKTIENGESELLSCHAFT (DE) 1982-07-13 US disclosed
US-4259456-A CONTAINING SODIUM ALKANESULFONATE, A FILLER, AND MELAMINE OR GUANIDINE THE LION FAT & OIL CO., LTD. (JP) 1981-03-31 US disclosed
US-4136075-A ACRYLIC ACID AND ESTER COPOLYMER, THERMOSETTING, CROSSLINKING AGENT, COATINGS FOR METALS A. E. STALEY MANUFACTURING COMPANY (US) 1979-01-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12569911-B2 Composition for use in sintered molded bodies and sintered molded body TIA1, PUF60, RPL5 NPC1 1558/4885RAB9A 3084/4885MAPT 356/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.