Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.68 |
| ▸ | RAB9A | P51151 | 4/20 | 0.68 |
| ▸ | MAPT | P10636 | 3/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.68 |
| ▸ | HTT | P42858 | 2/20 | 0.68 |
| ▸ | BCL6 | P41182 | 1/20 | 0.66 |
| ▸ | GAA | P10253 | 4/20 | 0.63 |
| ▸ | MEN1 | O00255 | 2/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.63 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.56 |
| ▸ | RELA | Q04206 | 1/20 | 0.56 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.56 |
| ▸ | CA12 | O43570 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL183118 | 1.00 | NPC1 (0.68) | NPC1RAB9AMAPTKMT2AHTT | |
| Hydrochloric Acid SCHEMBL9457998 | 0.98 | NPC1 (0.66) | NPC1RAB9AMAPTKMT2AHTT | |
| Arsenic SCHEMBL28153612 | 0.98 | NPC1 (0.66) | NPC1RAB9AMAPTKMT2AHTT | |
| SCHEMBL29079539 | 0.96 | MAPT (0.64) | NPC1RAB9AMAPTKMT2AHTT | |
| SCHEMBL2253957 | 0.95 | GAA (0.69) | NPC1RAB9AMAPTKMT2AHTT | |
| Aniline SCHEMBL27966308 | 0.94 | MAPT (0.62) | NPC1RAB9AMAPTKMT2AHTT | |
| SCHEMBL10910614 | 0.88 | CA12 (0.68) | NPC1RAB9AMAPTKMT2AHTT | |
| SCHEMBL29610073 | 0.86 | GAA (0.74) | NPC1RAB9AMAPTKMT2AHTT | |
| SCHEMBL14869446 | 0.86 | GAA (0.74) | NPC1RAB9AMAPTKMT2AHTT | |
| SCHEMBL796156 | 0.86 | BCL6 (0.61) | NPC1RAB9AMAPTKMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114929924-A | Chemical activation of self-passivated metals | 斯瓦戈洛克公司 | 2022-08-19 | — | — | CN | disclosed |