Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRY1 | Q16526 | 6/20 | 0.44 |
| ▸ | CRY2 | Q49AN0 | 6/20 | 0.44 |
| ▸ | PER2 | O15055 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
| ▸ | MMP13 | P45452 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17055854 | 0.83 | CRY1 (0.46) | CRY1CRY2PER2ALDH1A1MEN1 | |
| SCHEMBL12376988 | 0.83 | CRY1 (0.46) | CRY1CRY2PER2ALDH1A1MEN1 | |
| SCHEMBL26471765 | 0.83 | CRY1 (0.46) | CRY1CRY2PER2ALDH1A1MEN1 | |
| SCHEMBL15627010 | 0.78 | CRY1 (0.46) | CRY1CRY2PER2ALDH1A1MEN1 | |
| SCHEMBL18312162 | 0.74 | CRY1 (0.38) | CRY1CRY2PER2ALDH1A1MEN1 | |
| SCHEMBL18312607 | 0.73 | MEN1 (0.43) | CRY1CRY2PER2ALDH1A1MEN1 | |
| SCHEMBL10510602 | 0.73 | MEN1 (0.43) | CRY1CRY2PER2ALDH1A1MEN1 | |
| SCHEMBL2867976 | 0.72 | — | — | |
| SCHEMBL25809976 | 0.72 | — | — | |
| SCHEMBL18312549 | 0.72 | MEN1 (0.31) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016201225-A1 | ARYL DIHYDRO-2H-BENZO[B][1,4]OXAZINE SULFONAMIDE AND RELATED COMPOUNDS FOR USE AS AGONISTS OF RORY AND THE TREATMENT OF DISEASE | LYCERA CORPORATION (US) | 2016-12-15 | — | — | WO | disclosed |