Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 9/20 | 0.42 |
| ▸ | ADAM10 | O14672 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP3 | P08254 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.33 |
| ▸ | ATXN2 | Q99700 | 2/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL203759 | 0.94 | PRCP (0.43) | PRCPADAM10MMP2MMP3MMP9 | |
| SCHEMBL2707808 | 0.94 | PRCP (0.43) | PRCPADAM10MMP2MMP3MMP9 | |
| SCHEMBL2710081 | 0.92 | PRCP (0.41) | PRCPADAM10MMP2MMP3MMP9 | |
| SCHEMBL2706697 | 0.86 | PRCP (0.41) | PRCPADAM10MMP2MMP3MMP9 | |
| SCHEMBL204341 | 0.86 | PRCP (0.41) | PRCPADAM10MMP2MMP3MMP9 | |
| SCHEMBL2707006 | 0.86 | ADAM10 (0.42) | PRCPADAM10MMP2MMP3MMP9 | |
| SCHEMBL206727 | 0.86 | ADAM10 (0.42) | PRCPADAM10MMP2MMP3MMP9 | |
| SCHEMBL8749781 | 0.85 | PRCP (0.37) | PRCPADAM10MMP2MMP3MMP9 | |
| SCHEMBL14982876 | 0.85 | PRCP (0.39) | PRCPADAM10MMP2MMP3MMP9 | |
| SCHEMBL2757203 | 0.83 | PRCP (0.39) | PRCPADAM10MMP2MMP3MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016199049-A1 | PROCESS FOR THE PREPARATION OF LEDIPASVIR | HETERO RESEARCH FOUNDATION (IN) | 2016-12-15 | — | — | WO | disclosed |