Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 6/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | RARA | P10276 | 2/20 | 0.40 |
| ▸ | RARG | P13631 | 1/20 | 0.40 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 3/20 | 0.37 |
| ▸ | THRA | P10827 | 2/20 | 0.37 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.37 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.36 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16428906 | 0.86 | SOAT1 (0.47) | RARBRARARARGPTPN11FFAR4 | |
| SCHEMBL9399803 | 0.85 | RARB (0.57) | RARBRARARARGHRH3TSHR | |
| SCHEMBL9399219 | 0.85 | RARB (0.57) | RARBRARARARGHRH3TSHR | |
| SCHEMBL18314304 | 0.84 | FFAR4 (0.39) | RARBRARARARGPTPN11FFAR4 | |
| SCHEMBL17806146 | 0.83 | THRA (0.42) | THRBTHRANR5A1TSHRS1PR1 | |
| SCHEMBL10978244 | 0.83 | PTPN11 (0.49) | RARBRARARARGPTPN11THRB | |
| SCHEMBL10979375 | 0.83 | PTPN11 (0.49) | RARBRARARARGPTPN11THRB | |
| SCHEMBL10978234 | 0.83 | PTPN11 (0.49) | RARBRARARARGPTPN11THRB | |
| SCHEMBL19423207 | 0.83 | RARB (0.41) | RARBCNR2PTPN11THRBTHRA | |
| SCHEMBL19423232 | 0.83 | RARB (0.41) | RARBCNR2PTPN11THRBTHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016201283-A1 | ANTIFUNGAL AGENTS | CIDARA THERAPEUTICS, INC. (US) | 2016-12-15 | — | — | WO | disclosed |