Pyruvate

Pyruvate

SCHEMBL1831472

CC(=O)C(=O)O.CNCCO

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.37
MEN1 O00255 1/20 0.37
USP2 O75604 1/20 0.37
MAPT P10636 1/20 0.37
KMT2A Q03164 1/20 0.37
KDM4E B2RXH2 2/20 0.33
TSHR P16473 2/20 0.32
GAA P10253 1/20 0.32
CYP3A4 P08684 1/20 0.32
KISS1R Q969F8 1/20 0.32
ALOX15 P16050 1/20 0.30
LMNA P02545 1/20 0.30
THPO P40225 1/20 0.30
FFAR3 O14843 1/20 0.30
LCK P06239 1/20 0.30
FYN P06241 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetic Acid SCHEMBL1832152 0.89
Oxalic Acid SCHEMBL1837735 0.89 KDM4E (0.39) ALDH1A1MEN1USP2MAPTKMT2A
Bicarbonate SCHEMBL600163 0.86
Bicarbonate SCHEMBL1830889 0.86 MEN1 (0.36) ALDH1A1MEN1USP2MAPTKMT2A
Diethanolamine SCHEMBL1837947 0.81 KDM4E (0.39) ALDH1A1MEN1USP2MAPTKMT2A
Glycolic Acid SCHEMBL1831337 0.81 LDHA (0.35) ALDH1A1MEN1USP2MAPTKMT2A
SCHEMBL6247615 0.80 CARM1 (0.37) ALDH1A1MEN1USP2MAPTKMT2A
SCHEMBL15225 0.80
Propionic Acid SCHEMBL1834959 0.79 FFAR3 (0.53) ALDH1A1MEN1USP2MAPTKMT2A
Succinic Acid SCHEMBL1833489 0.79 EGLN1 (0.47) KDM4ETSHRLMNAFFAR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070185330-A1 Liquids THE UNIVERSITY OF YORK (GB) 2007-08-09 US claimed
US-9328220-B2 Liquids INNOVIA FILMS LIMITED (GB) 2016-05-03 US disclosed
US-8992798-B2 Liquids INNOVIA FILMS LIMITED (GB) 2015-03-31 US disclosed
US-8784686-B2 Liquids INNOVIA FILMS LIMITED (GB) 2014-07-22 US disclosed
US-20140187684-A1 LIQUIDS INNOVIA FILMS LIMITED (GB) 2014-07-03 US disclosed
US-20110257433-A1 LIQUIDS THE UNIVERSITY OF YORK (GB) 2011-10-20 US disclosed
EP-2322497-A1 Ionic liquids comprising nitrogen containing cations Innovia Films Limited (GB) 2011-05-18 EP disclosed
CN-101316810-A Ionic liquids BIONIQS LTD (GB) 2008-12-03 CN disclosed
US-20080221361-A1 Ionic Liquids BIONIQS LIMITED (GB) 2008-09-11 US disclosed
US-20070185330-A1 Liquids THE UNIVERSITY OF YORK (GB) 2007-08-09 US disclosed