Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 5/20 | 0.38 |
| ▸ | BRD2 | P25440 | 4/20 | 0.38 |
| ▸ | BRD3 | Q15059 | 4/20 | 0.38 |
| ▸ | FFAR2 | O15552 | 2/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.36 |
| ▸ | EZH2 | Q15910 | 2/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TTK | P33981 | 1/20 | 0.36 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18317135 | 0.80 | BRD4 (0.42) | BRD4BRD2BRD3EZH2NR3C1 | |
| SCHEMBL18317486 | 0.80 | BRD4 (0.41) | ALDH1A1MAPTKMT2ABRD4BRD2 | |
| SCHEMBL18317422 | 0.78 | ALDH1A1 (0.39) | ALDH1A1MAPTKMT2ABRD4BRD2 | |
| SCHEMBL16896954 | 0.72 | AKR1C3 (0.42) | ALDH1A1MAPTKMT2ABRD4BRD2 | |
| SCHEMBL18317121 | 0.71 | BRD4 (0.44) | BRD4BRD2BRD3CYP3A4CYP2C9 | |
| SCHEMBL18317269 | 0.69 | BRD4 (0.44) | ALDH1A1BRD4BRD2BRD3CYP3A4 | |
| SCHEMBL18378608 | 0.69 | BRD4 (0.53) | BRD4BRD2BRD3CYP3A4CYP2C9 | |
| SCHEMBL18317117 | 0.69 | BRD4 (0.43) | ALDH1A1BRD4BRD2BRD3EZH2 | |
| SCHEMBL18317734 | 0.69 | BRD4 (0.52) | BRD4BRD2BRD3CYP3A4CYP2C9 | |
| SCHEMBL18317126 | 0.69 | BRD4 (0.41) | BRD4BRD2BRD3CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160368906-A1 | BICYCLIC HETEROCYCLIC DERIVATIVES AS BROMODOMAIN INHIBITORS | ORION CORPORATION (FI) | 2016-12-22 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160368906-A1 | BICYCLIC HETEROCYCLIC DERIVATIVES AS BROMODOMAIN INHIBITORS | BRD1, BRD2, BRD3 | ALDH1A1 2949/4885MAPT 2737/4885KMT2A 1208/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.