SCHEMBL18319699

SCHEMBL18319699

CC(=O)N[C@H](C)Cc1cn(C(=O)O)cn1

nearest known ligand 0.46

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
MTNR1A P48039 5/20 0.40
MTNR1B P49286 5/20 0.40
ACACB O00763 12/20 0.39
CPB2 Q96IY4 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5147283 0.85 CPB2 (0.39) CPB2
SCHEMBL5795636 0.80 CPB2 (0.39) ACACBCPB2
SCHEMBL594580 0.78 CPB2 (0.42) CPB2
Hydrochloric Acid SCHEMBL11418503 0.77 CPB2 (0.41) CPB2
Hydrochloric Acid SCHEMBL1521823 0.77 CPB2 (0.41) CPB2
Hydrochloric Acid SCHEMBL3428343 0.76 CPB2 (0.40) CPB2
SCHEMBL16727751 0.75 CPB2 (0.48) CPB2
SCHEMBL7131533 0.75 CPB2 (0.35) CPB2
SCHEMBL4727798 0.73 CYP1A2 (0.45) CPB2
SCHEMBL4726518 0.73 CYP1A2 (0.45) CPB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240066124-A1 REDUCING VISCOSITY OF PHARMACEUTICAL FORMULATIONS AMGEN INC. (US) 2024-02-29 US disclosed
US-11813328-B2 Methods for reducing the viscosity of liquid pharmaceutical formulations comprising therapeutic proteins AMGEN INC. (US) 2023-11-14 US disclosed
EP-3909611-B1 REDUCING VISCOSITY OF PHARMACEUTICAL FORMULATIONS AMGEN INC (US) 2023-08-30 EP disclosed
EP-3909611-A1 REDUCING VISCOSITY OF PHARMACEUTICAL FORMULATIONS Amgen Inc. (US) 2021-11-17 EP disclosed
EP-3209332-B1 REDUCING VISCOSITY OF PHARMACEUTICAL FORMULATIONS AMGEN INC (US) 2021-05-26 EP disclosed
US-9980919-B2 Preparation of pH-responsive nanoparticles and promoted delivery of anticancer drugs into deep tumor tissues and application thereof NATIONAL TSING HUA UNIVERSITY (TW) 2018-05-29 US disclosed
US-20170333559-A1 REDUCING VISCOSITY OF PHARMACEUTICAL FORMULATIONS AMGEN INC. (US) 2017-11-23 US disclosed
EP-3209332-A1 REDUCING VISCOSITY OF PHARMACEUTICAL FORMULATIONS Amgen Inc. (US) 2017-08-30 EP disclosed
US-20160367489-A1 PREPARATION OF pH-RESPONSIVE NANOPARTICLES AND PROMOTED DELIVERY OF ANTICANCER DRUGS INTO DEEP TUMOR TISSUES AND APPLICATION THEREOF NATIONAL TSING HUA UNIVERSITY (TW) 2016-12-22 US disclosed