Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 11/20 | 0.65 |
| ▸ | SLC2A3 | P11169 | 10/20 | 0.65 |
| ▸ | SLC2A4 | P14672 | 9/20 | 0.65 |
| ▸ | SLC2A2 | P11168 | 4/20 | 0.58 |
| ▸ | LMNA | P02545 | 4/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.53 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.53 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.53 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18320980 | 0.92 | SLC2A1 (0.70) | SLC2A1SLC2A3SLC2A4SLC2A2LMNA | |
| SCHEMBL18320989 | 0.91 | SLC2A1 (0.69) | SLC2A1SLC2A3SLC2A4SLC2A2 | |
| SCHEMBL18320780 | 0.91 | SLC2A1 (0.79) | SLC2A1SLC2A3SLC2A4SLC2A2 | |
| SCHEMBL18320820 | 0.91 | SLC2A1 (0.68) | SLC2A1SLC2A3SLC2A4SLC2A2 | |
| SCHEMBL18320796 | 0.91 | SLC2A1 (0.68) | SLC2A1SLC2A3SLC2A4SLC2A2MEN1 | |
| SCHEMBL18320949 | 0.90 | SLC2A1 (0.64) | SLC2A1SLC2A3SLC2A4SLC2A2 | |
| SCHEMBL18320799 | 0.89 | SLC2A1 (0.72) | SLC2A1SLC2A3SLC2A4SLC2A2 | |
| SCHEMBL18320824 | 0.89 | SLC2A1 (0.66) | SLC2A1SLC2A3SLC2A4SLC2A2 | |
| SCHEMBL18320982 | 0.89 | SLC2A1 (0.65) | SLC2A1SLC2A3SLC2A4SLC2A2 | |
| SCHEMBL18320568 | 0.88 | SLC2A1 (0.65) | SLC2A1SLC2A3SLC2A4SLC2A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016202898-A1 | GLUCOSE TRANSPORT INHIBITORS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2016-12-22 | — | — | WO | claimed |
| WO-2016202898-A1 | GLUCOSE TRANSPORT INHIBITORS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2016-12-22 | — | — | WO | disclosed |