SCHEMBL18320796

SCHEMBL18320796

Cc1cccc(-c2cc(C(=O)Nc3c(C)nn(Cc4ccc(C#N)cc4)c3C)c3ccccc3n2)c1

nearest known ligand 0.68

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
SLC2A1 P11166 17/20 0.68
SLC2A3 P11169 16/20 0.68
SLC2A4 P14672 15/20 0.68
SLC2A2 P11168 7/20 0.61
MEN1 O00255 1/20 0.53
KMT2A Q03164 1/20 0.53
PTGER4 P35408 1/20 0.51
KDM4E B2RXH2 1/20 0.49
HPGD P15428 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18320989 0.94 SLC2A1 (0.69) SLC2A1SLC2A3SLC2A4SLC2A2PTGER4
SCHEMBL18320820 0.94 SLC2A1 (0.68) SLC2A1SLC2A3SLC2A4SLC2A2PTGER4
SCHEMBL18320799 0.92 SLC2A1 (0.72) SLC2A1SLC2A3SLC2A4SLC2A2PTGER4
SCHEMBL18320824 0.92 SLC2A1 (0.66) SLC2A1SLC2A3SLC2A4SLC2A2PTGER4
SCHEMBL18320547 0.92 SLC2A1 (0.74) SLC2A1SLC2A3SLC2A4SLC2A2MEN1
SCHEMBL18320982 0.91 SLC2A1 (0.65) SLC2A1SLC2A3SLC2A4SLC2A2PTGER4
SCHEMBL18320545 0.91 SLC2A1 (0.65) SLC2A1SLC2A3SLC2A4SLC2A2MEN1
SCHEMBL18320563 0.91 SLC2A1 (0.65) SLC2A1SLC2A3SLC2A4SLC2A2MEN1
SCHEMBL18320568 0.91 SLC2A1 (0.65) SLC2A1SLC2A3SLC2A4SLC2A2PTGER4
SCHEMBL18320962 0.90 SLC2A1 (0.65) SLC2A1SLC2A3SLC2A4SLC2A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2016202898-A1 GLUCOSE TRANSPORT INHIBITORS BAYER PHARMA AKTIENGESELLSCHAFT (DE) 2016-12-22 WO claimed