Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | SLC40A1 | Q9NP59 | 2/20 | 0.36 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.33 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.33 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.33 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.33 |
| ▸ | CDC7 | O00311 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.32 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL458978 | 0.84 | KDM4E (0.44) | KDM4EL3MBTL1TDP1KMT2AALDH1A1 | |
| SCHEMBL2003887 | 0.70 | ALDH1A1 (0.44) | KDM4EL3MBTL1PARP1MAP2K1CLK4 | |
| SCHEMBL13043597 | 0.68 | CCR1 (0.45) | L3MBTL1 | |
| SCHEMBL5799150 | 0.67 | KDM4E (0.49) | KDM4EL3MBTL1SLC40A1SIRT3TDP1 | |
| SCHEMBL3577315 | 0.67 | KDM4E (0.53) | KDM4EL3MBTL1SIRT3TDP1HTT | |
| SCHEMBL607663 | 0.66 | KDM4E (0.57) | KDM4EL3MBTL1SLC40A1HTTKMT2A | |
| SCHEMBL2414115 | 0.66 | KDM4E (0.57) | KDM4EL3MBTL1SLC40A1PARP1HTT | |
| SCHEMBL30688511 | 0.66 | KDM4E (0.57) | KDM4EL3MBTL1SLC40A1PARP1HTT | |
| SCHEMBL29381262 | 0.66 | KDM4E (0.57) | KDM4EL3MBTL1SLC40A1HTTKMT2A | |
| SCHEMBL1694892 | 0.66 | RET (0.46) | KDM4EL3MBTL1SLC40A1SIRT3TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016202898-A1 | GLUCOSE TRANSPORT INHIBITORS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2016-12-22 | — | — | WO | claimed |
| WO-2016202898-A1 | GLUCOSE TRANSPORT INHIBITORS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2016-12-22 | — | — | WO | disclosed |