Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | CASP1 | P29466 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | GABRP | O00591 | 1/20 | 0.38 |
| ▸ | GABRD | O14764 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.38 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.38 |
| ▸ | GABRE | P78334 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18320550 | 0.89 | KDM4E (0.40) | KDM4EALDH1A1HPGDSMN1; SMN2CASP1 | |
| SCHEMBL3657512 | 0.85 | IDO1 (0.44) | KDM4EALDH1A1HPGDSMN1; SMN2CASP1 | |
| SCHEMBL17267944 | 0.80 | ALDH1A1 (0.48) | KDM4EALDH1A1HPGDSMN1; SMN2CASP1 | |
| SCHEMBL17267922 | 0.80 | KDM4E (0.41) | KDM4EALDH1A1HPGDSMN1; SMN2CASP1 | |
| SCHEMBL461627 | 0.78 | POLB (0.46) | KDM4EALDH1A1HPGDSMN1; SMN2CASP1 | |
| SCHEMBL14946419 | 0.77 | KDM4E (0.38) | KDM4EALDH1A1HPGDSMN1; SMN2CASP1 | |
| SCHEMBL14946515 | 0.73 | KDM4E (0.76) | KDM4EALDH1A1HPGDSMN1; SMN2CASP1 | |
| SCHEMBL2807043 | 0.70 | KDM4E (0.48) | KDM4EALDH1A1GABRPGABRDGABRA1 | |
| SCHEMBL30987774 | 0.70 | KDM4E (0.45) | KDM4EALDH1A1GAAGABRPGABRD | |
| SCHEMBL27273060 | 0.70 | KDM4E (0.45) | KDM4EALDH1A1GAAGABRPGABRD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016202898-A1 | GLUCOSE TRANSPORT INHIBITORS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2016-12-22 | — | — | WO | disclosed |