Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 5/20 | 0.76 |
| ▸ | SLC2A3 | P11169 | 4/20 | 0.76 |
| ▸ | SLC2A2 | P11168 | 3/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.65 |
| ▸ | MEN1 | O00255 | 4/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.65 |
| ▸ | POLB | P06746 | 3/20 | 0.65 |
| ▸ | BRCA1 | P38398 | 2/20 | 0.65 |
| ▸ | RECQL | P46063 | 2/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.65 |
| ▸ | SLC2A4 | P14672 | 3/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | CASP1 | P29466 | 1/20 | 0.58 |
| ▸ | CASP7 | P55210 | 1/20 | 0.58 |
| ▸ | SCD | O00767 | 1/20 | 0.58 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.58 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18320705 | 0.88 | SLC2A1 (0.76) | SLC2A1SLC2A3SLC2A2KMT2ATDP1 | |
| SCHEMBL18320805 | 0.86 | SLC2A1 (1.00) | SLC2A1SLC2A3SLC2A2ALDH1A1HSD17B10 | |
| SCHEMBL16832934 | 0.85 | SLC2A1 (0.81) | SLC2A1SLC2A3SLC2A2ALDH1A1HSD17B10 | |
| SCHEMBL16832205 | 0.84 | SLC2A1 (0.78) | SLC2A1SLC2A3SLC2A2ALDH1A1HSD17B10 | |
| SCHEMBL16834042 | 0.84 | SLC2A1 (0.78) | SLC2A1SLC2A3SLC2A2ALDH1A1HSD17B10 | |
| SCHEMBL16832354 | 0.83 | SLC2A1 (0.77) | SLC2A1SLC2A3SLC2A2ALDH1A1HSD17B10 | |
| SCHEMBL18320586 | 0.83 | SLC2A1 (0.68) | SLC2A1SLC2A3SLC2A2ALDH1A1HSD17B10 | |
| SCHEMBL16833339 | 0.83 | SLC2A1 (0.76) | SLC2A1SLC2A3SLC2A2ALDH1A1HSD17B10 | |
| SCHEMBL16832438 | 0.82 | SLC2A1 (0.72) | SLC2A1SLC2A3SLC2A2ALDH1A1HSD17B10 | |
| SCHEMBL18321237 | 0.82 | SLC2A1 (0.67) | SLC2A1SLC2A3SLC2A2SLC2A4TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016202898-A1 | GLUCOSE TRANSPORT INHIBITORS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2016-12-22 | — | — | WO | claimed |
| WO-2016202898-A1 | GLUCOSE TRANSPORT INHIBITORS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2016-12-22 | — | — | WO | disclosed |