Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | HPGD | P15428 | 3/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | CASP1 | P29466 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | CASP7 | P55210 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | SLC26A6 | Q9BXS9 | 10/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18320719 | 0.81 | KDM4E (0.62) | KDM4EALDH1A1HPGDSMN1; SMN2CASP1 | |
| SCHEMBL18320759 | 0.80 | KDM4E (0.61) | KDM4EALDH1A1HPGDSMN1; SMN2CASP1 | |
| SCHEMBL17712776 | 0.71 | KDM4E (0.56) | KDM4EALDH1A1HPGDSMN1; SMN2GAA | |
| SCHEMBL18694772 | 0.70 | ALDH1A1 (0.63) | KDM4EALDH1A1HPGDSMN1; SMN2GAA | |
| SCHEMBL8832176 | 0.69 | IDO1 (0.53) | KDM4EALDH1A1HPGDSMN1; SMN2CASP1 | |
| SCHEMBL11818968 | 0.69 | KDM4E (0.49) | KDM4EALDH1A1HPGDSMN1; SMN2CASP1 | |
| SCHEMBL11819884 | 0.68 | KDM4E (0.48) | KDM4EALDH1A1HPGDSMN1; SMN2CASP1 | |
| SCHEMBL5961528 | 0.68 | KMT2A (0.55) | KDM4EALDH1A1HPGDSMN1; SMN2CASP1 | |
| SCHEMBL18716551 | 0.67 | ALDH1A1 (0.52) | KDM4EALDH1A1HPGDSMN1; SMN2CASP1 | |
| SCHEMBL6293949 | 0.67 | KDM4E (0.46) | KDM4EALDH1A1HPGDSMN1; SMN2CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016202898-A1 | GLUCOSE TRANSPORT INHIBITORS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2016-12-22 | — | — | WO | disclosed |