Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.54 |
| ▸ | HPGD | P15428 | 4/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | CFTR | P13569 | 1/20 | 0.45 |
| ▸ | DHODH | Q02127 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.43 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15936293 | 0.89 | ALDH1A1 (0.58) | ALDH1A1KDM4EHPGDNPSR1MAPT | |
| SCHEMBL2484301 | 0.86 | KDM4E (0.55) | ALDH1A1KDM4EHPGDNPSR1MAPT | |
| SCHEMBL7518100 | 0.83 | KDM4E (0.55) | ALDH1A1KDM4EHPGDMAPTMEN1 | |
| SCHEMBL23909566 | 0.83 | PTPN1 (0.51) | ALDH1A1KDM4EHPGDNPSR1MAPT | |
| SCHEMBL2152502 | 0.81 | ALDH1A1 (0.56) | ALDH1A1KDM4EHPGDNPSR1MAPT | |
| SCHEMBL3946512 | 0.79 | TSHR (0.52) | ALDH1A1KDM4EHPGDNPSR1MAPT | |
| SCHEMBL5315678 | 0.79 | KDM4E (0.58) | ALDH1A1KDM4EHPGDNPSR1MAPT | |
| SCHEMBL5364915 | 0.79 | ALDH1A1 (0.58) | ALDH1A1KDM4EHPGDNPSR1MAPT | |
| SCHEMBL27636776 | 0.79 | HPGD (0.49) | ALDH1A1KDM4EHPGDNPSR1MAPT | |
| SCHEMBL1539120 | 0.78 | ALDH1A1 (0.66) | ALDH1A1KDM4EHPGDNPSR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016202898-A1 | GLUCOSE TRANSPORT INHIBITORS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2016-12-22 | — | — | WO | disclosed |