Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY2 | P41231 | 10/20 | 0.52 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.52 |
| ▸ | P2RY6 | Q15077 | 7/20 | 0.51 |
| ▸ | P2RY1 | P47900 | 2/20 | 0.51 |
| ▸ | P2RY4 | P51582 | 3/20 | 0.50 |
| ▸ | P2RY14 | Q15391 | 3/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5566439 | 0.87 | SLC28A1 (0.58) | P2RY2P2RY12P2RY6P2RY1P2RY4 | |
| SCHEMBL5561799 | 0.87 | SLC28A1 (0.58) | P2RY2P2RY12P2RY6P2RY1P2RY4 | |
| SCHEMBL5566443 | 0.87 | SLC28A1 (0.58) | P2RY2P2RY12P2RY6P2RY1P2RY4 | |
| SCHEMBL2984123 | 0.87 | SLC28A1 (0.58) | P2RY2P2RY12P2RY6P2RY1P2RY4 | |
| SCHEMBL5561796 | 0.87 | SLC28A1 (0.58) | P2RY2P2RY12P2RY6P2RY1P2RY4 | |
| SCHEMBL10703901 | 0.86 | P2RY2 (0.57) | P2RY2P2RY6P2RY4P2RY14 | |
| SCHEMBL10704922 | 0.86 | P2RY2 (0.57) | P2RY2P2RY6P2RY4P2RY14 | |
| SCHEMBL9069552 | 0.83 | TK2 (0.53) | P2RY2P2RY12P2RY1 | |
| SCHEMBL2995484 | 0.83 | SLC28A1 (0.61) | P2RY2P2RY6P2RY1P2RY4P2RY14 | |
| SCHEMBL17670528 | 0.83 | P2RY2 (0.60) | P2RY2P2RY6P2RY4P2RY14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3310918-A1 | POLYNUCLEOTIDE AGENTS TARGETING HYDROXYACID OXIDASE (GLYCOLATE OXIDASE, HAO1) AND METHODS OF USE THEREOF | Alnylam Pharmaceuticals, Inc. (US) | 2018-04-25 | — | — | EP | disclosed |
| WO-2016205323-A1 | POLYNUCLEOTDE AGENTS TARGETING HYDROXYACID OXIDASE (GLYCOLATE OXIDASE, HAO1) AND METHODS OF USE THEREOF | ALNYLAM PHARMACEUTICALS, INC. (US) | 2016-12-22 | — | — | WO | disclosed |