Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK2 | O00142 | 4/20 | 0.53 |
| ▸ | P2RY12 | Q9H244 | 3/20 | 0.48 |
| ▸ | CA12 | O43570 | 4/20 | 0.46 |
| ▸ | CA1 | P00915 | 4/20 | 0.46 |
| ▸ | CA2 | P00918 | 4/20 | 0.46 |
| ▸ | CA9 | Q16790 | 4/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.46 |
| ▸ | P2RY2 | P41231 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.43 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.43 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.43 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9069522 | 0.96 | CA12 (0.49) | TK2P2RY12CA12CA1CA2 | |
| SCHEMBL25402244 | 0.95 | LMNA (0.50) | TK2P2RY12P2RY2LMNATHRB | |
| SCHEMBL5566835 | 0.92 | CA12 (0.47) | P2RY12CA12CA1CA2CA9 | |
| SCHEMBL5531486 | 0.91 | TK2 (0.61) | TK2P2RY12P2RY2SLC28A1SLC28A2 | |
| SCHEMBL7398474 | 0.91 | SLC28A1 (0.44) | TK2P2RY2LMNATHRBSMN1; SMN2 | |
| SCHEMBL5531119 | 0.91 | TK2 (0.61) | TK2P2RY12P2RY2SLC28A1SLC28A2 | |
| SCHEMBL18166816 | 0.91 | TLR4 (0.46) | TK2P2RY12CA12CA1CA2 | |
| SCHEMBL5561799 | 0.86 | SLC28A1 (0.58) | P2RY12P2RY2SLC28A1SLC28A2SLC29A1 | |
| SCHEMBL5566439 | 0.86 | SLC28A1 (0.58) | P2RY12P2RY2SLC28A1SLC28A2SLC29A1 | |
| SCHEMBL2984123 | 0.86 | SLC28A1 (0.58) | P2RY12P2RY2SLC28A1SLC28A2SLC29A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5583117-A | CARDIOVASCULAR, NERVOUS SYSTEM DISORDERS; DIABETES | PRO-NEURON, INC. (US) | 1996-12-10 | — | — | US | disclosed |