Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | MIF | P14174 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzene SCHEMBL11510532 | 0.86 | MIF (0.55) | CYP3A4TSHRMIFTDP1MAPK1 | |
| SCHEMBL245090 | 0.86 | MIF (0.55) | CYP3A4TSHRMIFTDP1MAPK1 | |
| SCHEMBL19459346 | 0.86 | MIF (0.55) | CYP3A4TSHRMIFTDP1MAPK1 | |
| SCHEMBL5925 | 0.86 | — | — | |
| SCHEMBL1332539 | 0.86 | — | — | |
| Pyridine SCHEMBL28157864 | 0.84 | TDP1 (0.44) | CYP3A4TSHRTDP1NAPRTMAPK1 | |
| Hydrochloric Acid SCHEMBL10918138 | 0.84 | MIF (0.52) | CYP3A4TSHRMIFTDP1MAPK1 | |
| Water SCHEMBL2017190 | 0.84 | MIF (0.52) | CYP3A4TSHRMIFTDP1MAPK1 | |
| Hydrochloric Acid SCHEMBL10809249 | 0.84 | MIF (0.52) | CYP3A4TSHRMIFTDP1MAPK1 | |
| Hydrogen Sulfide SCHEMBL2017797 | 0.84 | MIF (0.52) | CYP3A4TSHRMIFTDP1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8865664-B2 | Hydrophobically enhanced aminoglycosides | UNIVERSITY OF MANITOBA (CA) | 2014-10-21 | — | — | US | disclosed |
| US-20110178037-A1 | HYDROPHOBICALLY ENHANCED AMINOGLYCOSIDES | UNIVERSITY OF MANITOBA (CA) | 2011-07-21 | — | — | US | disclosed |
| EP-2318422-A2 | HYDROPHOBICALLY ENHANCED AMINOGLYCOSIDES | The University of Manitoba (US) | 2011-05-11 | — | — | EP | disclosed |
| WO-2010004433-A2 | HYDROPHOBICALLY ENHANCED AMINOGLYCOSIDES | UNIVERSITY OF MANITOBA (CA) | 2010-01-14 | — | — | WO | disclosed |
| US-5252482-A | Precursor of a C-terminal amidated calcitonin | SUNTORY LIMITED (JP) | 1993-10-12 | — | — | US | disclosed |
| EP-0095350-B1 | A METHOD OF PRODUCING HUMAN GAMMA-INTERFERON-LIKE POLIPEPTIDE | SUNTORY KABUSHIKI KAISHA (JP) | 1991-02-27 | — | — | EP | disclosed |
| EP-0095351-B1 | A PRECURSOR OF A C-TERMINAL AMIDATED PEPTIDE AND PRODUCTION THEREOF | SUNTORY KABUSHIKI KAISHA, also known as SUNTORY LTD. (JP) | 1989-11-08 | — | — | EP | disclosed |
| US-4638069-A | PESTICIDES | CIBA-GEIGY CORPORATION (US) | 1987-01-20 | — | — | US | disclosed |
| EP-0095350-A2 | A method of producing human gamma-interferon-like polipeptide | SUNTORY KABUSHIKI KAISHA (JP) | 1983-11-30 | — | — | EP | disclosed |
| EP-0095351-A2 | A precursor of a C-terminal amidated peptide and production thereof | SUNTORY KABUSHIKI KAISHA, also known as SUNTORY LTD. (JP) | 1983-11-30 | — | — | EP | disclosed |
| EP-0056721-A2 | Chemical synthesis apparatus for preparation of polynucleotides | ens BIO LOGICALS INC. (CA) | 1982-07-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110178037-A1 | HYDROPHOBICALLY ENHANCED AMINOGLYCOSIDES | SLC7A1, SLC47A1, MRPL21 | CYP3A4 2885/4885TSHR 4175/4885MIF 1572/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.